Sollte ich retinoic acid in der Schwangerschaft meiden? | VeriMom
All‑trans‑retinoic acid (tretinoin, CAS 302-79-4) has a harmonised reproductive hazard classification (Repr. 1A/1B, H360/D) in ECHA records and is prohibited in cosmetic products in the EU; oral retinoids are established human teratogens and retinoic acid acts through well‑characterised retinoid receptor (RAR/RXR) signalling that causes embryopathy. Topical absorption is measurable but generally low, so exposure from typical cosmetic topical use is low but not zero. (ECHA; FDA product literature; mechanistic and teratogenic literature).
ECHA regulatory hazard statements
- •H360D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Ist retinoic acid in der Schwangerschaft sicher?
- All‑trans‑retinoic acid (tretinoin, CAS 302-79-4) has a harmonised reproductive hazard classification (Repr. 1A/1B, H360/D) in ECHA records and is prohibited in cosmetic products in the EU; oral retinoids are established human teratogens and retinoic acid acts through well‑characterised retinoid receptor (RAR/RXR) signalling that causes embryopathy. Topical absorption is measurable but generally low, so exposure from typical cosmetic topical use is low but not zero. (ECHA; FDA product literature; mechanistic and teratogenic literature).
- Ist retinoic acid während des Stillens sicher?
- Direct data on excretion of topical tretinoin into human milk are limited/ inconclusive, but the compound is systemically active and a retinoid; because of systemic teratogenicity and potential for transfer, caution is advised. Systemic absorption from topical use is generally low, so breast‑milk exposure is likely low but not well‑quantified in humans. (ECHA; FDA/label information; limited pharmacokinetic studies).
- Ist retinoic acid sicher für Babyhaut?
- Tretinoin is a known teratogenic retinoid with well‑defined RAR/RXR activity. Infant skin (0–3 yr) has higher surface‑area‑to‑weight and an immature barrier, so exposure score is increased by +1 relative to adults when topical absorption is measurable. Because tretinoin is prohibited in cosmetics in the EU and flagged as H360, it is not appropriate for use on infant skin. (ECHA; SCCS/CIR context; pediatric exposure considerations).
- Wie bewertet VeriMom retinoic acid?
- VeriMom bewertet retinoic acid mit 13/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu retinoic acid?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu retinoic acid basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.