Sollte ich quaternium-15 in der Schwangerschaft meiden? | VeriMom
Quaternium‑15 (CAS 4080‑31‑3 / mixed cis/trans and cis isomer CAS variants) has been regulated as a CMR (toxic for reproduction) concern in the EU and has been moved into Annex II (prohibited in cosmetics) following classification of the cis‑isomer as a reproductive toxicant; harmonised/authoritative sources and regulatory reviews report reproductive/teratogenic findings in animals. Because of that regulatory action (EU Annex II / Commission Regulation amending 1223/2009) and reported animal findings, the hazard score is 2. Mechanistically, quaternium‑15 is a formaldehyde‑releasing preservative and there are animal reproduction/developmental toxicity findings reported in regulatory reviews, so mechanism is scored as demonstrated (2). Topical cosmetic exposures give low but measurable systemic exposure for most formaldehyde releasers, therefore exposure is scored 1 for pregnancy. (Sources: EU Commission Regulation / Annex II amendment; SCCS/CIR/regulatory reviews; animal studies.)
ECHA regulatory hazard statements
- •H361
- •H361D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Ist quaternium-15 in der Schwangerschaft sicher?
- Quaternium‑15 (CAS 4080‑31‑3 / mixed cis/trans and cis isomer CAS variants) has been regulated as a CMR (toxic for reproduction) concern in the EU and has been moved into Annex II (prohibited in cosmetics) following classification of the cis‑isomer as a reproductive toxicant; harmonised/authoritative sources and regulatory reviews report reproductive/teratogenic findings in animals. Because of that regulatory action (EU Annex II / Commission Regulation amending 1223/2009) and reported animal findings, the hazard score is 2. Mechanistically, quaternium‑15 is a formaldehyde‑releasing preservative and there are animal reproduction/developmental toxicity findings reported in regulatory reviews, so mechanism is scored as demonstrated (2). Topical cosmetic exposures give low but measurable systemic exposure for most formaldehyde releasers, therefore exposure is scored 1 for pregnancy. (Sources: EU Commission Regulation / Annex II amendment; SCCS/CIR/regulatory reviews; animal studies.)
- Ist quaternium-15 während des Stillens sicher?
- Same hazard/mechanism as for pregnancy (regulatory classification and animal data). With typical topical cosmetic use, systemic absorption is expected to be low; therefore breastmilk exposure potential is low but not zero — exposure scored 1. No specific breast‑milk transfer studies located in the reviewed sources.
- Ist quaternium-15 sicher für Babyhaut?
- Hazard and mechanism remain driven by the same regulatory and animal evidence (EU prohibition based on CMR classification of the cis‑isomer and reported developmental toxicity). Exposure score is increased by +1 for infants (per instruction) because infant skin barrier immaturity and higher surface‑area‑to‑weight ratio make low but measurable percutaneous absorption more relevant; therefore baby exposure scored 2. Note: quaternium‑15 is also a known skin sensitizer in humans, increasing concern for infant dermal irritation/allergy.
- Wie bewertet VeriMom quaternium-15?
- VeriMom bewertet quaternium-15 mit 20/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu quaternium-15?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu quaternium-15 basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.