Sollte ich pregnenolone acetate in der Schwangerschaft meiden? | VeriMom

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Pregnancy-safe ingredients that serve a similar function:

FAQ

Ist pregnenolone acetate in der Schwangerschaft sicher?

Hazard: animal and mechanistic evidence that pregnenolone and related steroids modulate sex‑steroid signalling and can affect reproductive tissues (peer‑reviewed studies), and multiple supplier SDSs/self‑classifications list H361 (suspected of damaging fertility/unborn child). Mechanism: demonstrated steroid/estrogen receptor modulation and biological activity in animal models (pregnenolone effects on uterine ER expression and developmental effects in embryos). Exposure: topical cosmetic use historically (e.g., 1% creams) and the molecule is lipophilic so low but measurable dermal absorption is plausible for adults. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/30411422/?utm_source=openai))

Ist pregnenolone acetate während des Stillens sicher?

Hazard & mechanism: because the acetate is converted to pregnenolone (a steroid precursor) and pregnenolone shows endocrine activity in animals, there is potential risk to the nursing infant if significant systemic maternal exposure occurs; mechanism (steroid activity and ability to alter hormone signalling) is demonstrated in animal studies. Exposure: dermal use by nursing mothers would likely give low but measurable maternal systemic exposure (therefore low infant exposure via breastmilk is plausible), but direct data on lactation transfer are lacking. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/30411422/?utm_source=openai))

Ist pregnenolone acetate sicher für Babyhaut?

Hazard & mechanism: same concerns as for pregnancy — conversion to an active steroid (pregnenolone) and demonstrated endocrine/reproductive effects in animal models justify a suspected hazard for infants. Exposure: infant (0–3 yr) skin has higher surface‑area‑to‑weight and less mature barrier; therefore dermal exposure potential is increased (+1 exposure score). Direct infant dermal safety data are not available. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/30411422/?utm_source=openai))

Wie bewertet VeriMom pregnenolone acetate?

VeriMom bewertet pregnenolone acetate mit 20/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.

Was sind schwangerschaftssichere Alternativen zu pregnenolone acetate?

Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu pregnenolone acetate basierend auf ähnlicher Funktion.