Sollte ich podophyllum peltatum rhizome/root extract in der Schwangerschaft meiden? | VeriMom

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FAQ

Ist podophyllum peltatum rhizome/root extract in der Schwangerschaft sicher?

Animal reproductive/embryotoxicity and human case reports with topical podophyllum/podophyllotoxin have led to clinical contraindication in pregnancy; regulatory listings (ECHA substance records list podophyllum resin under reproductive concern) and product monographs contraindicate use in pregnancy. Sources: epidemiologic/clinical review (PubMed/PMC), product monograph, ECHA substance info.

Ist podophyllum peltatum rhizome/root extract während des Stillens sicher?

Podophyllotoxin/podophyllin are not recommended during lactation; product monographs note excretion in human milk or lack of data and advise against breastfeeding during treatment. Mechanism is antimitotic (demonstrated), and systemic absorption from topical application can occur. See product monograph and clinical guidance.

Ist podophyllum peltatum rhizome/root extract sicher für Babyhaut?

Hazard is driven by the parent antimitotic compound (podophyllotoxin) so h/m same as adults; dermal absorption is documented for topical podophyllotoxin/podophyllin formulations so infant exposure from topical cosmetic use on baby skin is higher (immature barrier and SA:BW) — exposure score increased by +1 for 0–3 yr.

Wie bewertet VeriMom podophyllum peltatum rhizome/root extract?

VeriMom bewertet podophyllum peltatum rhizome/root extract mit 33/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.

Was sind schwangerschaftssichere Alternativen zu podophyllum peltatum rhizome/root extract?

Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu podophyllum peltatum rhizome/root extract basierend auf ähnlicher Funktion.