VeriMomSollte ich phenolphthalein in der Schwangerschaft meiden? | VeriMom
Phenolphthalein has harmonised CLP classifications for reproductive toxicity including H360 (per ECHA brief profile / Annex VI) and H361f (suspected of damaging fertility), which meets the criterion for H360-level evidence → h=3. There is experimental evidence of estrogenic activity/in vitro endocrine effects and genotoxicity in animal/in vitro studies supporting a demonstrated mechanism (m=2). For typical topical cosmetic use systemic absorption is likely low but measurable, so exposure is scored e=1. Sources: ECHA harmonised classification, NTP/animal carcinogenicity/genotoxicity literature, in vitro estrogenic reports.
ECHA regulatory hazard statements
- •H350
- •H361F
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Ist phenolphthalein in der Schwangerschaft sicher?
- Phenolphthalein has harmonised CLP classifications for reproductive toxicity including H360 (per ECHA brief profile / Annex VI) and H361f (suspected of damaging fertility), which meets the criterion for H360-level evidence → h=3. There is experimental evidence of estrogenic activity/in vitro endocrine effects and genotoxicity in animal/in vitro studies supporting a demonstrated mechanism (m=2). For typical topical cosmetic use systemic absorption is likely low but measurable, so exposure is scored e=1. Sources: ECHA harmonised classification, NTP/animal carcinogenicity/genotoxicity literature, in vitro estrogenic reports.
- Ist phenolphthalein während des Stillens sicher?
- Harmonised classification includes reproductive concerns (H361f) and the substance has animal/genotoxic and in vitro estrogenic data; breastfeeding is scored h=2 because harmonised H361 (suspected reproductive hazard) supports 'suspected' rather than confirmed systemic teratogen for lactation exposure. Mechanistic data (in vitro estrogenic activity, genotoxicity) give m=2. Systemic absorption from topical use is likely low but measurable, so milk transfer risk is low but not negligible (e=1).
- Ist phenolphthalein sicher für Babyhaut?
- For infant topical exposure (0–3 yr) the hazard score is maintained at h=2 (suspected reproductive/toxic effects per harmonised H361; H360-level evidence applies to developmental systemic teratogenesis but infant-skin–specific teratogenic data are not available so h is not escalated to 3). No infant‑specific mechanistic data identified, so m=0 (do not increase m without infant-specific evidence). Adult topical absorption judged low but measurable (adult e=1), and per instruction baby skin exposure is increased by +1 → e=2. Overall infant dermal exposure could be higher due to immature barrier and higher surface-area-to-weight ratio. Sources cited below.
- Wie bewertet VeriMom phenolphthalein?
- VeriMom bewertet phenolphthalein mit 20/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu phenolphthalein?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu phenolphthalein basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.