VeriMomSollte ich nitrous oxide in der Schwangerschaft meiden? | VeriMom
Dinitrogen oxide (nitrous oxide, CAS 10024-97-2) now has a harmonised CLP classification in the EU as Repr. 1B (H360Df) (Official Journal / CLP Annex VI update), which by calibration requires h=3. The mechanistic literature shows demonstrated inactivation of methionine‑synthase / perturbation of folate‑B12 pathways in animals and human cells (PubMed), supporting m=2. For normal topical cosmetic use the expected topical dermal/systemic absorption from a finished cosmetic product is negligible, so exposure (e) for pregnancy from topical use is scored 0; however inhalation (medical or recreational) is a separate, high‑exposure route and is outside routine cosmetic topical exposure assumptions.
ECHA regulatory hazard statements
- •H360DF
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Ist nitrous oxide in der Schwangerschaft sicher?
- Dinitrogen oxide (nitrous oxide, CAS 10024-97-2) now has a harmonised CLP classification in the EU as Repr. 1B (H360Df) (Official Journal / CLP Annex VI update), which by calibration requires h=3. The mechanistic literature shows demonstrated inactivation of methionine‑synthase / perturbation of folate‑B12 pathways in animals and human cells (PubMed), supporting m=2. For normal topical cosmetic use the expected topical dermal/systemic absorption from a finished cosmetic product is negligible, so exposure (e) for pregnancy from topical use is scored 0; however inhalation (medical or recreational) is a separate, high‑exposure route and is outside routine cosmetic topical exposure assumptions.
- Ist nitrous oxide während des Stillens sicher?
- Harmonised Repr.1B (H360Df) applies to the substance (h=3). Mechanism is the same as for pregnancy (methionine synthase / folate interference documented) so m=2. For typical cosmetic topical application breastfeeding exposure is expected to be negligible (e=0). Inhalation/medical exposure would increase exposure but is not typical for cosmetics.
- Ist nitrous oxide sicher für Babyhaut?
- Hazard remains h=3 because of the harmonised Repr.1B classification. Mechanistic evidence (B12/methionine synthase inhibition, folate perturbation) supports m=2. For infant skin (0–3 yr) assume increased potential exposure relative to adults; since the substance is not completely non‑absorbable and infants have a less mature barrier the exposure score is increased by +1 (adult e=0 → infant e=1). Topical cosmetic use still would normally produce negligible systemic uptake, but infant susceptibility and increased surface‑area‑to‑weight justify the +1 increase.
- Wie bewertet VeriMom nitrous oxide?
- VeriMom bewertet nitrous oxide mit 27/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu nitrous oxide?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu nitrous oxide basierend auf ähnlicher Funktion.
Prüfe jede Zutatenliste in 2 Sekunden
Lade VeriMom kostenlos — scanne jedes Produkt und sieh sofort die Schwangerschafts-Sicherheitsbewertung.
Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.