VeriMomSollte ich methylene di-t-butylcresol in der Schwangerschaft meiden? | VeriMom
ECHA lists 6,6'-di-tert‑butyl‑2,2'‑methylenedi‑p‑cresol (CAS 119‑47‑1) with a harmonised classification for reproductive toxicity (Repr. 1B, H360F — “May damage fertility”), which by the scoring rules yields h=3. Animal reproductive/developmental findings are reported in regulatory dossiers (developmental NOAEL/LOAEL in non‑rodents in EPA/registration material), but a specific molecular reproductive mechanism is not established in the literature (m=1). For routine topical cosmetic use dermal absorption is likely low but not zero (lipophilic high‑molecular phenolic antioxidant), so exposure for a pregnant adult is scored as low but measurable (e=1). Sources: ECHA harmonised classification and registration/assessment data and regulatory toxicology summaries.
ECHA regulatory hazard statements
- •H360F
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FAQ
- Ist methylene di-t-butylcresol in der Schwangerschaft sicher?
- ECHA lists 6,6'-di-tert‑butyl‑2,2'‑methylenedi‑p‑cresol (CAS 119‑47‑1) with a harmonised classification for reproductive toxicity (Repr. 1B, H360F — “May damage fertility”), which by the scoring rules yields h=3. Animal reproductive/developmental findings are reported in regulatory dossiers (developmental NOAEL/LOAEL in non‑rodents in EPA/registration material), but a specific molecular reproductive mechanism is not established in the literature (m=1). For routine topical cosmetic use dermal absorption is likely low but not zero (lipophilic high‑molecular phenolic antioxidant), so exposure for a pregnant adult is scored as low but measurable (e=1). Sources: ECHA harmonised classification and registration/assessment data and regulatory toxicology summaries.
- Ist methylene di-t-butylcresol während des Stillens sicher?
- Same harmonised reproductive classification (Repr. 1B, H360F) applies and supports a high hazard score (h=3). No clear mechanistic data specific to lactational transfer was found (m=1). For topical cosmetic use, maternal dermal exposure is expected to be low but measurable; breastmilk transfer is plausible for lipophilic compounds but was not documented in available studies, so exposure is scored as low (e=1). Regulatory guidance therefore flags this substance for reproductive concern.
- Ist methylene di-t-butylcresol sicher für Babyhaut?
- Hazard remains high because of the harmonised Repr.1B/H360F classification (h=3). No infant‑specific mechanism data was identified (m=1). Because infant skin (0–3 yr) has higher absorption per body weight and an immature barrier, exposure score is increased by +1 relative to adults (adult e=1 → baby e=2) where dermal absorption is measurable. No infant dermal studies were located to justify changing hazard or mechanism scores.
- Wie bewertet VeriMom methylene di-t-butylcresol?
- VeriMom bewertet methylene di-t-butylcresol mit 27/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu methylene di-t-butylcresol?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu methylene di-t-butylcresol basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.