VeriMomSollte ich methoxyethanol acetate in der Schwangerschaft meiden? | VeriMom
Harmonised CLP classification for 2‑methoxyethyl acetate (CAS 110‑49‑6) is Repr. 1B, H360FD (harmonised Annex VI), therefore per your calibration this is h=3. The compound is known to be metabolised to 2‑methoxyethanol (EGME), which has demonstrated reproductive toxicity in animals and occupational settings (mechanism via the glycol‑ether metabolites is established), so mechanism is scored 2. Dermal absorption is documented as measurable for glycol ether esters, so topical exposure is low but measurable (e=1). Sources: ECHA harmonised classification and EU Cosmetic Regulation Annex II (prohibited).
ECHA regulatory hazard statements
- •H360FD
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FAQ
- Ist methoxyethanol acetate in der Schwangerschaft sicher?
- Harmonised CLP classification for 2‑methoxyethyl acetate (CAS 110‑49‑6) is Repr. 1B, H360FD (harmonised Annex VI), therefore per your calibration this is h=3. The compound is known to be metabolised to 2‑methoxyethanol (EGME), which has demonstrated reproductive toxicity in animals and occupational settings (mechanism via the glycol‑ether metabolites is established), so mechanism is scored 2. Dermal absorption is documented as measurable for glycol ether esters, so topical exposure is low but measurable (e=1). Sources: ECHA harmonised classification and EU Cosmetic Regulation Annex II (prohibited).
- Ist methoxyethanol acetate während des Stillens sicher?
- Same hazard basis applies for lactation: harmonised Repr.1B (H360FD) and metabolic conversion to EGME indicate a confirmed reproductive hazard potential for mother/infant exposure (h=3). Mechanistic evidence of metabolite‑mediated toxicity supports m=2. For topical use, dermal uptake is measurable but not high (e=1); data on milk transfer are limited but given systemic absorption and classification concern, lactational exposure is plausible and caution is warranted.
- Ist methoxyethanol acetate sicher für Babyhaut?
- Hazard remains h=3 because of harmonised H360FD. Mechanistic concerns (metabolic conversion to EGME) remain (m=2). Exposure is increased for infants (per your rule +1) because infant skin has higher absorption/SA:weight and the parent compound is dermally absorbable — adult e=1 → baby e=2. The substance is explicitly prohibited in cosmetics under EU Cosmetic Regulation Annex II, so it should not be present in products for infants/children.
- Wie bewertet VeriMom methoxyethanol acetate?
- VeriMom bewertet methoxyethanol acetate mit 20/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu methoxyethanol acetate?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu methoxyethanol acetate basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.