VeriMomSollte ich imidazole in der Schwangerschaft meiden? | VeriMom
Imidazole (CAS 288-32-4) is listed by ECHA with a harmonised classification for developmental toxicity (Category 1B, H360D), which by your scoring rules is H360-level evidence -> h=3. The mechanistic basis for the classification is not well‐characterised in publicly available dossiers, so mechanism is scored as theoretical/uncertain (m=1). Dermal/topical cosmetic exposure would likely give low but measurable systemic exposure for an adult (e=1) unless formulation/route increases uptake; this is supported by ECHA/EU classification and multiple safety data sheets listing H360D.
ECHA regulatory hazard statements
- •H360D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Ist imidazole in der Schwangerschaft sicher?
- Imidazole (CAS 288-32-4) is listed by ECHA with a harmonised classification for developmental toxicity (Category 1B, H360D), which by your scoring rules is H360-level evidence -> h=3. The mechanistic basis for the classification is not well‐characterised in publicly available dossiers, so mechanism is scored as theoretical/uncertain (m=1). Dermal/topical cosmetic exposure would likely give low but measurable systemic exposure for an adult (e=1) unless formulation/route increases uptake; this is supported by ECHA/EU classification and multiple safety data sheets listing H360D.
- Ist imidazole während des Stillens sicher?
- Because imidazole has a harmonised developmental/teratogenic classification (H360D, Category 1B) the hazard for lactation/breastfeeding is elevated and scored h=3 per your rule for H360-level evidence. No specific human milk transfer or breastfeeding studies were identified in the sources consulted, so mechanistic evidence is limited (m=1). Maternal topical use would most likely give low but measurable systemic exposure (e=1) in adults; therefore potential transfer in milk cannot be excluded.
- Ist imidazole sicher für Babyhaut?
- Hazard remains H360-level (h=3) because of ECHA harmonised developmental classification. Mechanistic data are limited (m=1). For baby skin (0–3 yr) exposure scoring increases by +1 compared with adults when the adult exposure is measurable: adult e=1 -> infant e=2 because infant skin has higher surface-area-to-weight and an immature barrier, increasing potential absorption.
- Wie bewertet VeriMom imidazole?
- VeriMom bewertet imidazole mit 27/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu imidazole?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu imidazole basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.