Sollte ich ibuprofen in der Schwangerschaft meiden? | VeriMom
Ibuprofen (CAS 15687-27-1) is an NSAID with human/animal evidence of adverse fetal effects (fetal renal dysfunction/oligohydramnios and premature ductus arteriosus closure) prompting an FDA warning to avoid NSAID use at ≈20 weeks gestation and later; this supports a 'suspected' reproductive hazard (h=2). The mechanism is demonstrated (prostaglandin inhibition → fetal renal/ductus arteriosus effects), so m=2. Topical/cosmetic use yields low but measurable systemic exposure vs oral use, so exposure for topical cosmetic use is low (e=1). Sources: FDA, MotherToBaby/NCBI, ECHA substance information.
ECHA regulatory hazard statements
- •H360
- •H361
- •H362
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Ist ibuprofen in der Schwangerschaft sicher?
- Ibuprofen (CAS 15687-27-1) is an NSAID with human/animal evidence of adverse fetal effects (fetal renal dysfunction/oligohydramnios and premature ductus arteriosus closure) prompting an FDA warning to avoid NSAID use at ≈20 weeks gestation and later; this supports a 'suspected' reproductive hazard (h=2). The mechanism is demonstrated (prostaglandin inhibition → fetal renal/ductus arteriosus effects), so m=2. Topical/cosmetic use yields low but measurable systemic exposure vs oral use, so exposure for topical cosmetic use is low (e=1). Sources: FDA, MotherToBaby/NCBI, ECHA substance information.
- Ist ibuprofen während des Stillens sicher?
- Available clinical guidance and reviews indicate very low transfer of ibuprofen into human milk and no documented infant harm for usual maternal doses; therefore no reproductive/breastfeeding hazard is indicated (h=0, m=0). Milk transfer is measurable but low, so e=1. Sources: MotherToBaby (NCBI), NHS Specialist Pharmacy Service; clinical references note ibuprofen is generally compatible with breastfeeding.
- Ist ibuprofen sicher für Babyhaut?
- Hazard (h=2) is carried over because systemic reproductive/toxicity evidence for ibuprofen exists (see pregnancy summary). Per instructions, infant-specific hazard or mechanism were not found so h and m are not increased beyond adult evidence (m=2). Topical exposure for infants is increased relative to adults (immature barrier and higher surface-area-to-weight) so exposure is raised by +1 (adult e=1 → baby e=2). No infant-specific studies were found showing different hazard; precautionary higher exposure score applied.
- Wie bewertet VeriMom ibuprofen?
- VeriMom bewertet ibuprofen mit 20/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu ibuprofen?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu ibuprofen basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.