VeriMomSollte ich hydroxycortisone succinate in der Schwangerschaft meiden? | VeriMom
EU/ECHA substance information shows harmonised classification for reproductive toxicity (Repr. 1A H360 and Repr.2 H361) for hydrocortisone 21‑hemisuccinate (CAS 2203-97-6), so this meets the criterion for confirmed reproductive hazard (h=3). The mechanism is glucocorticoid action with demonstrated ability of systemic corticosteroids to affect fetal development/placenta (m=2). For typical topical cosmetic use, systemic absorption is low (e=1), so exposure from normal topical cosmetic use is expected to be low but not zero. (Sources: ECHA brief profile / C&L inventory; guidance on topical corticosteroids in pregnancy).
ECHA regulatory hazard statements
- •H360
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Ist hydroxycortisone succinate in der Schwangerschaft sicher?
- EU/ECHA substance information shows harmonised classification for reproductive toxicity (Repr. 1A H360 and Repr.2 H361) for hydrocortisone 21‑hemisuccinate (CAS 2203-97-6), so this meets the criterion for confirmed reproductive hazard (h=3). The mechanism is glucocorticoid action with demonstrated ability of systemic corticosteroids to affect fetal development/placenta (m=2). For typical topical cosmetic use, systemic absorption is low (e=1), so exposure from normal topical cosmetic use is expected to be low but not zero. (Sources: ECHA brief profile / C&L inventory; guidance on topical corticosteroids in pregnancy).
- Ist hydroxycortisone succinate während des Stillens sicher?
- Because of the harmonised reproductive classification for the substance (see ECHA) and the known systemic effects of hydrocortisone, a conservative approach assigns h=3 for lactation context as well. Mechanistically, corticosteroids can distribute systemically and small amounts can appear in milk (m=2). For topical cosmetic application (not systemic therapy), milk exposure is generally low unless applied directly to the breast/nipple (e=1). (Sources: ECHA C&L brief profile; LactMed and NHS topical corticosteroid guidance).
- Ist hydroxycortisone succinate sicher für Babyhaut?
- Harmonised classification (ECHA) indicates reproductive hazard (h=3) for the substance; that harmonised CMR classification applies as the primary hazard signal. Mechanism remains hydrocortisone (glucocorticoid) activity (m=2). Dermal exposure and systemic uptake from baby skin are higher than adult per surface‑area‑to‑weight and immature barrier — therefore exposure score is increased by +1 versus adult topical use (adult e=1 → infant e=2). There is no infant‑specific innocuousness data for cosmetic use of this specific derivative. (Sources: ECHA brief profile; EDF/dermatology and guideline reviews on topical corticosteroids/pregnancy and child skin).
- Wie bewertet VeriMom hydroxycortisone succinate?
- VeriMom bewertet hydroxycortisone succinate mit 20/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu hydroxycortisone succinate?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu hydroxycortisone succinate basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.