VeriMomSollte ich hydroxyanasatil retinoate in der Schwangerschaft meiden? | VeriMom
No harmonised Annex VI CLP classification was found for CAS 127471-94-7, but the substance is a retinoic acid ester (structural class known to interact with retinoid receptors). Retinoids/retinoic acid are well‑characterised developmental toxicants via RAR/RXR-mediated mechanisms (SCCS and regulatory literature treat vitamin A / some retinoids as reproductive/developmental hazards). Because there is no harmonised H360 entry for this specific CAS and no published specific reproductive animal/human data located for 127471-94-7, hazard is scored as structural/class-based concern only (h=1) while mechanism is rated high (RAR agonism well characterized). Topical absorption from cosmetics is likely low but measurable, so exposure is scored as 1. (Sources: SCCS Vitamin A opinion; supplier/patent records identifying this compound as a retinoate.).
ECHA regulatory hazard statements
- •H360
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FAQ
- Ist hydroxyanasatil retinoate in der Schwangerschaft sicher?
- No harmonised Annex VI CLP classification was found for CAS 127471-94-7, but the substance is a retinoic acid ester (structural class known to interact with retinoid receptors). Retinoids/retinoic acid are well‑characterised developmental toxicants via RAR/RXR-mediated mechanisms (SCCS and regulatory literature treat vitamin A / some retinoids as reproductive/developmental hazards). Because there is no harmonised H360 entry for this specific CAS and no published specific reproductive animal/human data located for 127471-94-7, hazard is scored as structural/class-based concern only (h=1) while mechanism is rated high (RAR agonism well characterized). Topical absorption from cosmetics is likely low but measurable, so exposure is scored as 1. (Sources: SCCS Vitamin A opinion; supplier/patent records identifying this compound as a retinoate.).
- Ist hydroxyanasatil retinoate während des Stillens sicher?
- Same structural/class‑based concern applies for breastfeeding: no specific reproductive/lactation studies found for this CAS, but retinoids have a known RAR/RXR mechanism. Systemic exposure after topical use is expected to be low but potentially measurable; transfer into breast milk has not been reported for this specific substance. Therefore hazard = 1 (structural/class alert), mechanism = 3, exposure = 1 (low but measurable).
- Ist hydroxyanasatil retinoate sicher für Babyhaut?
- Infant skin (0–3 yr) has higher surface‑area‑to‑weight and an immature barrier; for a retinoate with measurable absorption in adults we increase exposure by +1 for babies. There are no infant‑specific toxicity or dermal developmental studies for this CAS, so hazard remains a structural/class alert (h=1) and mechanism remains retinoid receptor activity (m=3). Exposure is scored moderate (e=2) for baby skin due to increased per‑kg uptake from topical application.
- Wie bewertet VeriMom hydroxyanasatil retinoate?
- VeriMom bewertet hydroxyanasatil retinoate mit 33/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu hydroxyanasatil retinoate?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu hydroxyanasatil retinoate basierend auf ähnlicher Funktion.
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Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.