VeriMomSollte ich estradiol in der Schwangerschaft meiden? | VeriMom
Estradiol (17β‑estradiol, CAS 50-28-2) carries harmonised reproductive hazard classification (H360—may damage fertility or the unborn child) in EU classification sources and product SDSs, and medicinal product labeling/clinical guidance list estradiol as contraindicated in pregnancy. Estrogens cross the placenta and maternal/experimental studies show excess maternal estradiol alters fetal development. Topical/transdermal estradiol formulations are known to give systemic exposure, so topical cosmetic application with appreciable systemic absorption would expose the fetus. (ECHA classification/SDS; DailyMed drug labeling; animal and human studies).
ECHA regulatory hazard statements
- •H360
- •H360FD
- •H361
- •H362
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Ist estradiol in der Schwangerschaft sicher?
- Estradiol (17β‑estradiol, CAS 50-28-2) carries harmonised reproductive hazard classification (H360—may damage fertility or the unborn child) in EU classification sources and product SDSs, and medicinal product labeling/clinical guidance list estradiol as contraindicated in pregnancy. Estrogens cross the placenta and maternal/experimental studies show excess maternal estradiol alters fetal development. Topical/transdermal estradiol formulations are known to give systemic exposure, so topical cosmetic application with appreciable systemic absorption would expose the fetus. (ECHA classification/SDS; DailyMed drug labeling; animal and human studies).
- Ist estradiol während des Stillens sicher?
- Harmonised/label information and safety data sheets include H362 (may cause harm to breast‑fed children) and list lactation effects; clinical drug labels state estrogens are present in human milk and may reduce milk production and are contraindicated or advised against during breastfeeding. Estradiol is systemically bioactive and transfers into milk; topical/transdermal absorption can produce systemic levels. (ECHA/SDS; DailyMed; pharmacology literature).
- Ist estradiol sicher für Babyhaut?
- Hazard (H360/H362) is intrinsic to the parent hormone and applies to infants: estradiol is a potent estrogen with well‑characterized receptor activity and documented developmental effects in animal and human observational studies. Exposure via product applied to infant skin would be of high concern because estradiol is absorbable transdermally (used clinically as transdermal therapy) and infant skin has higher surface‑area‑to‑weight and immature barrier — exposure rating increased for infant skin. No infant‑safe cosmetic use is supported. (ECHA/SDS; clinical/transdermal product literature; peer‑reviewed studies on maternal estradiol effects).
- Wie bewertet VeriMom estradiol?
- VeriMom bewertet estradiol mit 0/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu estradiol?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu estradiol basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.