Sollte ich epichlorohydrin in der Schwangerschaft meiden? | VeriMom
Animal developmental and reproductive toxicity studies (one-generation and developmental studies) report adverse effects; ECHA registration dossier and EPA summaries document these findings and some C&L notifications list H361 (suspected reproductive toxicant). There is mechanistic evidence that epichlorohydrin is a reactive epoxide (genotoxic/alkylating) which plausibly underlies developmental/reproductive toxicity. Topical cosmetic exposure would be low but measurable; epichlorohydrin has a skin penetration (NIOSH skin notation) so systemic exposure is possible if used on skin. (Sources: ECHA registration dossier; PubMed study; EPA summary; NIOSH/NIOSH PEL page).
ECHA regulatory hazard statements
- •H350
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Ist epichlorohydrin in der Schwangerschaft sicher?
- Animal developmental and reproductive toxicity studies (one-generation and developmental studies) report adverse effects; ECHA registration dossier and EPA summaries document these findings and some C&L notifications list H361 (suspected reproductive toxicant). There is mechanistic evidence that epichlorohydrin is a reactive epoxide (genotoxic/alkylating) which plausibly underlies developmental/reproductive toxicity. Topical cosmetic exposure would be low but measurable; epichlorohydrin has a skin penetration (NIOSH skin notation) so systemic exposure is possible if used on skin. (Sources: ECHA registration dossier; PubMed study; EPA summary; NIOSH/NIOSH PEL page).
- Ist epichlorohydrin während des Stillens sicher?
- Same rationale as for pregnancy: animal data and regulatory dossiers indicate reproductive/developmental hazard (H361 notifications). Mechanistic genotoxic/reactive epoxide activity supports potential for systemic harm. Dermal absorption is possible so measurable maternal systemic exposure (and therefore theoretical transfer to breastmilk) cannot be excluded, though direct lactation-specific data are unavailable.
- Ist epichlorohydrin sicher für Babyhaut?
- Hazard and mechanism same as adults (animal reproductive/developmental effects; reactive epoxide chemistry). Because epichlorohydrin is skin-penetrant (NIOSH skin notation) and infant skin has higher surface-area-to-weight and immature barrier, exposure score is increased by +1 (adult e=1 → infant e=2). There are no infant-specific safety studies identified.
- Wie bewertet VeriMom epichlorohydrin?
- VeriMom bewertet epichlorohydrin mit 20/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu epichlorohydrin?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu epichlorohydrin basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.