VeriMomSollte ich chlorophene in der Schwangerschaft meiden? | VeriMom
Chlorophene (clorofene, CAS 120-32-1) has a harmonised CLP classification including H361f (suspected of damaging fertility), which supports a suspected reproductive hazard (h=2). Animal studies (NTP 2‑year gavage and other toxicology reports) show developmental/non‑reproductive toxic effects (including some non‑dose‑dependent developmental findings in rabbits and mutagenicity in vitro), supporting a demonstrated mechanistic concern (m=2). For typical topical cosmetic use exposure is expected to be low but measurable (e=1). Sources: ECHA harmonised CLP listing; NTP / toxicology studies; published safety assessments. (See sources.)
ECHA regulatory hazard statements
- •H351
- •H361F
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FAQ
- Ist chlorophene in der Schwangerschaft sicher?
- Chlorophene (clorofene, CAS 120-32-1) has a harmonised CLP classification including H361f (suspected of damaging fertility), which supports a suspected reproductive hazard (h=2). Animal studies (NTP 2‑year gavage and other toxicology reports) show developmental/non‑reproductive toxic effects (including some non‑dose‑dependent developmental findings in rabbits and mutagenicity in vitro), supporting a demonstrated mechanistic concern (m=2). For typical topical cosmetic use exposure is expected to be low but measurable (e=1). Sources: ECHA harmonised CLP listing; NTP / toxicology studies; published safety assessments. (See sources.)
- Ist chlorophene während des Stillens sicher?
- Harmonised H361 (and related regulatory assessments) indicate suspected effects on fertility/development (h=2). Mechanistic and toxicology data from animal studies and in vitro mutagenicity support a demonstrated concern (m=2). For topical use, maternal systemic exposure is expected to be low but measurable (e=1); no reliable data were found documenting transfer into breastmilk, so exposure via breastmilk cannot be ruled out. Sources: ECHA CLP listing; NTP and other toxicology literature.
- Ist chlorophene sicher für Babyhaut?
- Hazard is the same (h=2) because of the harmonised H361f and supporting animal/toxicology data. Mechanistic evidence from studies (mutagenicity/in vivo toxicity) supports m=2. Exposure score is increased by +1 for baby skin (adult e=1 → baby e=2) because chlorophene is a relatively lipophilic, absorbable phenolic antimicrobial (logP ≈4.3) and infants (0–3 yrs) have higher surface‑area‑to‑weight and an immature barrier, increasing per‑kg systemic exposure from topical application. No infant‑specific toxicokinetic or dermal absorption studies were identified. Sources: ECHA CLP; NTP/toxicology studies; product/physicochemical records.
- Wie bewertet VeriMom chlorophene?
- VeriMom bewertet chlorophene mit 20/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu chlorophene?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu chlorophene basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.