VeriMomSollte ich benzophenone-1 in der Schwangerschaft meiden? | VeriMom
Benzophenone-1 (2,4-dihydroxybenzophenone; CAS 131-56-6) has a harmonised ECHA classification for reproductive toxicity H361 (suspected of damaging fertility or the unborn child), which justifies h=2. Peer-reviewed in vitro and mechanistic studies show endocrine activity (estrogenic activity in MCF‑7 cells and inhibition of steroidogenic enzymes including 17β‑HSD3), supporting a demonstrated mechanism (m=2). As a small lipophilic UV‑filter with documented biological activity and use in topical products, dermal uptake is plausible and judged moderate for pregnancy exposure (e=2). Sources: ECHA C&L / substance profile; SCCS activity on BP‑1; PubMed mechanistic studies; CIR review.
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Ist benzophenone-1 in der Schwangerschaft sicher?
- Benzophenone-1 (2,4-dihydroxybenzophenone; CAS 131-56-6) has a harmonised ECHA classification for reproductive toxicity H361 (suspected of damaging fertility or the unborn child), which justifies h=2. Peer-reviewed in vitro and mechanistic studies show endocrine activity (estrogenic activity in MCF‑7 cells and inhibition of steroidogenic enzymes including 17β‑HSD3), supporting a demonstrated mechanism (m=2). As a small lipophilic UV‑filter with documented biological activity and use in topical products, dermal uptake is plausible and judged moderate for pregnancy exposure (e=2). Sources: ECHA C&L / substance profile; SCCS activity on BP‑1; PubMed mechanistic studies; CIR review.
- Ist benzophenone-1 während des Stillens sicher?
- Same hazard basis (ECHA harmonised H361) applies for lactation (h=2). Mechanistic data (in vitro estrogenic effects and inhibition of steroidogenic enzymes) indicate potential endocrine activity relevant to breast tissue and hormonal regulation (m=2). Exposure via systemic uptake from topical use is assessed as moderate (e=2), consistent with other benzophenone UV‑filters which show measurable absorption and systemic detection in biomonitoring studies (see cited literature).
- Ist benzophenone-1 sicher für Babyhaut?
- Hazard (h=2) and mechanistic (m=2) ratings follow the harmonised classification and the demonstrated endocrine activity. Exposure for infants (0–3 yr) is increased by one category compared with adults because immature/ thinner skin and higher surface‑area‑to‑weight ratio raise dermal uptake for ingredients with measurable absorption, so e=3. There is no infant‑specific evidence to increase h or m further.
- Wie bewertet VeriMom benzophenone-1?
- VeriMom bewertet benzophenone-1 mit 13/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu benzophenone-1?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu benzophenone-1 basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.