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Sollte ich basic yellow 57 in der Schwangerschaft meiden? | VeriMom

Animal developmental studies report fetal malformations at very high oral doses (developmental NOAEL corrected ≈237 mg/kg bw/day; adverse effects at 1000 mg/kg in rats), supporting suspected developmental hazard based on animal data. The ingredient does not have a harmonised H360 classification, but animal reproductive/developmental findings justify h=2 (suspected). Dermal absorption from representative cosmetic formulations is low but measurable in in vitro pig skin studies (2–4% bioavailable after 48 h) and reported cosmetic uses are primarily hair dyes at low concentrations, so exposure from normal topical cosmetic use is low but non‑negligible. (CIR safety assessment; SCCS summary; ECHA substance record).

ECHA regulatory hazard statements

  • H361D

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FAQ

Ist basic yellow 57 in der Schwangerschaft sicher?
Animal developmental studies report fetal malformations at very high oral doses (developmental NOAEL corrected ≈237 mg/kg bw/day; adverse effects at 1000 mg/kg in rats), supporting suspected developmental hazard based on animal data. The ingredient does not have a harmonised H360 classification, but animal reproductive/developmental findings justify h=2 (suspected). Dermal absorption from representative cosmetic formulations is low but measurable in in vitro pig skin studies (2–4% bioavailable after 48 h) and reported cosmetic uses are primarily hair dyes at low concentrations, so exposure from normal topical cosmetic use is low but non‑negligible. (CIR safety assessment; SCCS summary; ECHA substance record).
Ist basic yellow 57 während des Stillens sicher?
No human lactation studies were located. Animal developmental/reprotoxic findings indicate a suspected hazard (h=2). There is no evidence of a specific reproductive mechanism or documented transfer into milk; dermal systemic absorption from cosmetic use is low but measurable so maternal systemic exposure (and therefore potential, but likely low, transfer into breastmilk) is possible. (CIR; ECHA).
Ist basic yellow 57 sicher für Babyhaut?
Hazard score follows the animal developmental data (h=2). Mechanistic data for developmental/ endocrine modes of action were not identified (m=0). Measurable dermal bioavailability in in vitro skin studies (2–4% over 48 h) means exposure on infant skin is higher relative to adults due to immature barrier and higher surface‑area‑to‑weight; per scoring rules increase exposure by +1 giving e=2 for 0–3 y infants. No infant‑specific absorption studies were found. (CIR dermal absorption data; SCCS/CIR use‑levels).
Wie bewertet VeriMom basic yellow 57?
VeriMom bewertet basic yellow 57 mit 33/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
Was sind schwangerschaftssichere Alternativen zu basic yellow 57?
Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu basic yellow 57 basierend auf ähnlicher Funktion.

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Medizinischer Haftungsausschluss

Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.

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