VeriMomSollte ich aziridine in der Schwangerschaft meiden? | VeriMom
Aziridine (ethyleneimine, CAS 151-56-4) has harmonised/regulatory classifications and authoritative toxicology indicating mutagenic and carcinogenic properties (ECHA registration/C&L info, EPA/IRIS, IARC). Harmonised flags for reproductive hazard (suspected; H361 reported in regulatory sources) support 'suspected' reproductive hazard (h=2). The mechanism is well-supported as an alkylating/genotoxic agent (demonstrated genotoxicity/mutagenicity) so m=2. For topical exposure, aziridine is a small, reactive molecule with reported dermal absorption and clear systemic toxicity in occupational/animal data, so exposure from topical use would be at least measurable/moderate (e=2). Sources: ECHA dossier/C&L summaries, EPA IRIS/FACT sheet, NIOSH/NIH toxicology summaries, IARC summary.
ECHA regulatory hazard statements
- •H350
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Ist aziridine in der Schwangerschaft sicher?
- Aziridine (ethyleneimine, CAS 151-56-4) has harmonised/regulatory classifications and authoritative toxicology indicating mutagenic and carcinogenic properties (ECHA registration/C&L info, EPA/IRIS, IARC). Harmonised flags for reproductive hazard (suspected; H361 reported in regulatory sources) support 'suspected' reproductive hazard (h=2). The mechanism is well-supported as an alkylating/genotoxic agent (demonstrated genotoxicity/mutagenicity) so m=2. For topical exposure, aziridine is a small, reactive molecule with reported dermal absorption and clear systemic toxicity in occupational/animal data, so exposure from topical use would be at least measurable/moderate (e=2). Sources: ECHA dossier/C&L summaries, EPA IRIS/FACT sheet, NIOSH/NIH toxicology summaries, IARC summary.
- Ist aziridine während des Stillens sicher?
- Same hazard and mechanism rationale as pregnancy (suspected reproductive/teratogenic risk via genotoxic/alkylating activity). No specific human lactation transfer data located, but systemic toxicity and dermal absorption reported in authoritative sources imply measurable maternal exposure and potential for transfer into breastmilk (therefore e=2).
- Ist aziridine sicher für Babyhaut?
- Hazard and mechanism as above (h=2, m=2). Because infant skin (0–3 yr) has higher surface-area-to-weight and an immature barrier, exposure score increases by +1 relative to adult topical exposure (adult e=2 → baby e=3). There is no infant-specific toxicokinetic evidence to change hazard or mechanism scores, only exposure.
- Wie bewertet VeriMom aziridine?
- VeriMom bewertet aziridine mit 13/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu aziridine?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu aziridine basierend auf ähnlicher Funktion.
Prüfe jede Zutatenliste in 2 Sekunden
Lade VeriMom kostenlos — scanne jedes Produkt und sieh sofort die Schwangerschafts-Sicherheitsbewertung.
Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.