Sollte ich azadirachta indica seed extract in der Schwangerschaft meiden? | VeriMom

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FAQ

Ist azadirachta indica seed extract in der Schwangerschaft sicher?

Harmonised/regulatory and animal data justify a 'suspected' reproductive hazard. ECHA documentation and regulatory discussion identify margosa (Azadirachta indica) kernel/seed extracts with harmonised H361 (suspected of damaging fertility or the unborn child) for specific extracts prepared from kernels with aqueous + organic solvent processing. Multiple animal studies and reviews report antifertility, abortifacient and fetal/developmental effects (neonatal/fetal malformations, reduced fetal weight) associated with neem seed oil/azadirachtin in rodents, and mechanistic data include progesterone reduction and immune-mediated effects. For topical cosmetic use, dermal absorption is expected to be low but not zero, so exposure is scored as low but measurable. (ECHA CLH/Annex VI; animal/peer-reviewed studies).

Ist azadirachta indica seed extract während des Stillens sicher?

Same overall hazard/ mechanism as pregnancy: harmonised H361 for certain margosa/kernel extracts and animal evidence for reproductive effects from seed-derived neem preparations make this a suspected hazard for lactating people. There are no robust human lactation transfer data for cosmetic topical use; because systemic absorption from topical use is generally low but possible, exposure is scored low but measurable. Animal data indicate systemic effects after oral dosing of seed/seed-oil preparations (supporting potential for systemic exposure when dose or formulation allows).

Ist azadirachta indica seed extract sicher für Babyhaut?

Hazard and mechanism remain 'suspected' based on the same harmonised/regulatory classification and animal data tied to seed/kernel extracts. Exposure score is increased by +1 for infant skin (0–3 yr) because infant skin barrier/SA:body-weight considerations raise systemic uptake potential for topically applied ingredients that have any measurable absorption in adults; there are no infant-specific dermal toxicokinetic studies for cosmetic seed extracts. Apply caution for products intended for infants if the formulation contains seed/kernel-derived neem extracts.

Wie bewertet VeriMom azadirachta indica seed extract?

VeriMom bewertet azadirachta indica seed extract mit 20/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.

Was sind schwangerschaftssichere Alternativen zu azadirachta indica seed extract?

Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu azadirachta indica seed extract basierend auf ähnlicher Funktion.