Sollte ich acetanilid in der Schwangerschaft meiden? | VeriMom
Animal reproductive/developmental studies (OECD SIDS / repeated-dose and reproduction studies) report reproductive/developmental effects and NOAELs in rats; several manufacturer SDS also list H361 (suspected of damaging fertility or the unborn child), so acetanilide is reasonably suspected from animal data. Mechanistic data are limited — metabolism to aniline/phenolic metabolites is known (theoretical concern) but there is no well-characterised placental-transfer or endocrine-disruption mechanism for acetanilide in humans. Topical cosmetic absorption is expected to be low but measurable (low log Kow, used at low concentrations), so exposure from typical topical use is low but non‑zero.
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Ist acetanilid in der Schwangerschaft sicher?
- Animal reproductive/developmental studies (OECD SIDS / repeated-dose and reproduction studies) report reproductive/developmental effects and NOAELs in rats; several manufacturer SDS also list H361 (suspected of damaging fertility or the unborn child), so acetanilide is reasonably suspected from animal data. Mechanistic data are limited — metabolism to aniline/phenolic metabolites is known (theoretical concern) but there is no well-characterised placental-transfer or endocrine-disruption mechanism for acetanilide in humans. Topical cosmetic absorption is expected to be low but measurable (low log Kow, used at low concentrations), so exposure from typical topical use is low but non‑zero.
- Ist acetanilid während des Stillens sicher?
- Same animal evidence that supports a suspected reproductive/developmental hazard applies to lactation context (no human breastfeeding-specific safety data). Mechanistic concerns are theoretical (metabolism to aniline); topical absorption is likely low but measurable so maternal systemic exposure from cosmetics could be low but not zero, with potential for transfer into milk not well studied.
- Ist acetanilid sicher für Babyhaut?
- Hazard scoring follows the animal evidence (suspected reproductive/developmental hazard). Mechanistic evidence remains theoretical. Exposure score increased by +1 for infants (per instructions) because baby skin has higher surface-area-to-weight and an immature barrier and acetanilide has measurable (though limited) dermal absorption; thus infant exposure from topical products is moderate rather than low.
- Wie bewertet VeriMom acetanilid?
- VeriMom bewertet acetanilid mit 27/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu acetanilid?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu acetanilid basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.