Sollte ich 2-ethylhexanol in der Schwangerschaft meiden? | VeriMom
Animal developmental studies (NTP CD‑1 mouse developmental toxicity report and other GLP studies) report increased fetal skeletal variations/other developmental effects in mice following exposure, supporting a suspected reproductive/developmental hazard (h=2). A specific mechanistic pathway for reproductive effects is not well established in the literature (assigned m=1 for theoretical/partial mechanistic evidence). For typical topical cosmetic use dermal absorption is low but measurable (e=1), so systemic exposure from normal cosmetic use is expected to be low; however systemic maternal exposure caused the effects in high‑dose animal studies. Sources: NTP developmental study; EPA PPRTV summary; PubChem substance summary; ECHA registration dossier.
ECHA regulatory hazard statements
- •H361
- •H361D
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FAQ
- Ist 2-ethylhexanol in der Schwangerschaft sicher?
- Animal developmental studies (NTP CD‑1 mouse developmental toxicity report and other GLP studies) report increased fetal skeletal variations/other developmental effects in mice following exposure, supporting a suspected reproductive/developmental hazard (h=2). A specific mechanistic pathway for reproductive effects is not well established in the literature (assigned m=1 for theoretical/partial mechanistic evidence). For typical topical cosmetic use dermal absorption is low but measurable (e=1), so systemic exposure from normal cosmetic use is expected to be low; however systemic maternal exposure caused the effects in high‑dose animal studies. Sources: NTP developmental study; EPA PPRTV summary; PubChem substance summary; ECHA registration dossier.
- Ist 2-ethylhexanol während des Stillens sicher?
- Because animal developmental/reproductive evidence indicates suspected reproductive/developmental toxicity, breastfeeding was conservatively scored h=2 (suspected). There is no well‑documented human lactation/transfer data or well‑characterized mechanism (m=1). Dermal absorption from cosmetic use is low but measurable (e=1), implying low maternal systemic exposures and therefore low but non‑zero potential for milk transfer in the absence of direct human lactation data.
- Ist 2-ethylhexanol sicher für Babyhaut?
- Hazard (h=2) is carried over because animal developmental studies indicate suspected developmental/reproductive effects; there is no infant‑specific evidence to change hazard or mechanism scores. Mechanistic information remains limited (m=1). Exposure score is increased by +1 for baby skin (e=2) because infant skin has higher surface‑area‑to‑weight and an immature barrier and 2‑ethylhexanol is a small, somewhat lipophilic alcohol with measurable dermal absorption in models, so infant dermal exposure is plausibly higher than adult topical use.
- Wie bewertet VeriMom 2-ethylhexanol?
- VeriMom bewertet 2-ethylhexanol mit 27/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu 2-ethylhexanol?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu 2-ethylhexanol basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.