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HIGH RISK

Should I Avoid tetramethyl-1-hexadecen-3-ol During Pregnancy? | VeriMom

Reviewed by · Last reviewed

ECHA regulatory hazard statements

  • H361

What to use instead

Pregnancy-safe ingredients that serve a similar function:

Pregnancy-safe products to use instead

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Sources & references

Authoritative references used to score this ingredient.

Pregnancy-Safe Alternatives to tetramethyl-1-hexadecen-3-ol | VeriMom

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FAQ

Is tetramethyl-1-hexadecen-3-ol safe during pregnancy?
Animal reproductive/developmental findings are reported in authoritative safety reviews (one‑generation reproductive study summarized in the RIFM / Food and Chemical Toxicology assessment), supporting suspicion of reproductive hazard (animal data). No harmonised Annex VI CLP (H360) was found; many supplier SDSs list H361 but these appear to be self‑classifications rather than a harmonised classification. Exposures from typical topical cosmetic use are expected to be low but measurable. (Sources: RIFM/food chem tox review; supplier SDS summaries).
Is tetramethyl-1-hexadecen-3-ol safe while breastfeeding?
Same animal reproductive/developmental data apply as a potential concern for fertility/development; no specific data on lactational transfer or human breastfeeding studies were identified. Topical cosmetic exposures are expected to be low but measurable, so conservative classification follows the animal evidence. No mechanism or human data demonstrating transfer in milk were found.
Is tetramethyl-1-hexadecen-3-ol safe for baby skin?
Animal studies indicate reproductive/developmental effects at high doses (see RIFM review). For dermal exposure, adults have low but measurable absorption; because infant skin has higher surface‑area‑to‑weight and an immature barrier, exposure score is increased by +1 per your rules. No infant‑specific toxicokinetic data were identified.
How does VeriMom score tetramethyl-1-hexadecen-3-ol?
VeriMom scores tetramethyl-1-hexadecen-3-ol at 33/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to tetramethyl-1-hexadecen-3-ol?
See our curated list of pregnancy-safe alternatives to tetramethyl-1-hexadecen-3-ol based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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