VeriMomHIGH RISK
Should I Avoid spironolactone During Pregnancy? | VeriMom
Reviewed by VeriMom Editorial Team · Last reviewed
ECHA regulatory hazard statements
- •H360
What to use instead
Pregnancy-safe ingredients that serve a similar function:
Pregnancy-safe products to use instead
Products built around the safer ingredients above, scored "no known risks" or "low risk".
Mew mew tweet
100Mew mew tweet Cedar Spruce Baking Soda Free
L'Occitane
100L´Occitane Powder To-mousse Facial Exfoliator
Avero
100Avero Solid Deodorant
Unknown
100schmidts here now
Sustain Yourself
100Sustain Yourself Natural Deodorant
Bitamin
100Bitamin Natural Deodorant N'orange
Dr Teals's
99Dr Teals's Aluminum Free Deodorant Charcoal
900care
99Déodorant stick parfum embruns
HappySoaps
99Happysoaps Neutraal
Routine
99Routine The Curator
Sources & references
Authoritative references used to score this ingredient.
Pregnancy-Safe Alternatives to spironolactone | VeriMom
Ingredients — Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
See also
FAQ
- Is spironolactone safe during pregnancy?
- Spironolactone has a harmonised CLP reproductive toxicity classification (H360 — 'May damage fertility or the unborn child') on ECHA records/annex listings, and animal and case-report data support anti‑androgenic effects on fetal sexual development; mechanism is well characterised (anti‑androgenic activity demonstrated in vivo). Topical cosmetic use would usually give low systemic exposure compared with oral therapeutic dosing, so exposure from typical topical cosmetic use is judged low but measurable. Sources: ECHA CLP/harmonised listing, FDA product label, animal/human reports (PubMed/PMC).
- Is spironolactone safe while breastfeeding?
- Intrinsic hazard remains at H360 level (may damage the unborn child/fertility). Mechanism (anti‑androgenic activity / endocrine effects) is well characterised. Clinical/lactation databases (LactMed, NHS) report low transfer of spironolactone into breast milk and no consistent adverse effects in reported infants at therapeutic maternal doses, so exposure to a breastfed infant from maternal systemic dosing is generally low; for cosmetic topical use systemic levels would be expected to be lower still (low but potentially measurable).
- Is spironolactone safe for baby skin?
- The substance carries harmonised H360 (intrinsic reproductive hazard) so hazard score is 3. Mechanistic anti‑androgenic activity is well characterised. Exposure for infants (0–3 yr) is higher than adults for a given topical exposure because of immature barrier and higher surface‑area‑to‑weight; therefore exposure score is increased by one compared with adult topical use (adult topical e=1 → infant e=2). There is no infant‑specific evidence to change hazard or mechanism scores.
- How does VeriMom score spironolactone?
- VeriMom scores spironolactone at 13/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to spironolactone?
- See our curated list of pregnancy-safe alternatives to spironolactone based on similar function and a no-known-risks safety band.
Check every label in 2 seconds
Get VeriMom free — scan any product and see the pregnancy safety score instantly.
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.