Sollte ich sodium picramate in der Schwangerschaft meiden? | VeriMom
Harmonised classification for sodium picramate/picramic acid includes Repr. 1B H360F (“May damage fertility”) in ECHA/CLP-related registrations and dossiers; per your calibration H360→h=3. SCCS has evaluated picramic acid/sodium picramate for hair-dye use and set restricted maximum on-head concentration (0.6% in non-oxidative hair dyes), indicating systemic/repro concern driving the restriction. Evidence for a specific molecular reproductive mechanism is limited in available reviews (so m=1). Topical hair-dye use can lead to low but measurable systemic exposure in adults (SCCS restriction), so e=1.
ECHA regulatory hazard statements
- •H360F
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Ist sodium picramate in der Schwangerschaft sicher?
- Harmonised classification for sodium picramate/picramic acid includes Repr. 1B H360F (“May damage fertility”) in ECHA/CLP-related registrations and dossiers; per your calibration H360→h=3. SCCS has evaluated picramic acid/sodium picramate for hair-dye use and set restricted maximum on-head concentration (0.6% in non-oxidative hair dyes), indicating systemic/repro concern driving the restriction. Evidence for a specific molecular reproductive mechanism is limited in available reviews (so m=1). Topical hair-dye use can lead to low but measurable systemic exposure in adults (SCCS restriction), so e=1.
- Ist sodium picramate während des Stillens sicher?
- Harmonised classification (H360F) applies regardless of exposure route; therefore h=3. No robust data were located demonstrating mechanism or mammary‑transfer studies (m=1). Given likely limited systemic absorption from typical topical hair‑dye use but non-zero (SCCS restriction), maternal systemic exposure — and therefore potential, low breast‑milk exposure — is possible (e=1).
- Ist sodium picramate sicher für Babyhaut?
- Hazard (H360F) remains the relevant intrinsic property so h=3 (do not up‑rank hazard without infant‑specific evidence). Mechanistic evidence for a reproductive pathway is limited (m=1). Because infant skin has higher absorption per weight and immature barrier, and adult topical use shows measurable absorption, increase exposure by +1 for 0–3 yr (adult e=1 → baby e=2). No infant‑specific toxicokinetic or dermal absorption studies were found.
- Wie bewertet VeriMom sodium picramate?
- VeriMom bewertet sodium picramate mit 27/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu sodium picramate?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu sodium picramate basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.