VeriMomDois-je éviter salicylamide pendant la grossesse ? | VeriMom
ECHA REACH/registration data include Repr.2 / H361 notifications for salicylamide (CAS 65-45-2) submitted by registrants (not a harmonised Annex VI classification). This supports a 'suspected' reproductive hazard (h=2) but is not harmonised by the Commission. Mechanistic concern is class-based/theoretical (m=1) because salicylamide is a salicylate-related compound and salicylates are known to cross the placenta and be systemically available; direct mechanistic reproductive data for salicylamide are limited. Exposure from typical topical cosmetic use is expected to be low but measurable (evidence for dermal cosmetic exposure is limited), so e=1.
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- salicylamide est-il sûr pendant la grossesse ?
- ECHA REACH/registration data include Repr.2 / H361 notifications for salicylamide (CAS 65-45-2) submitted by registrants (not a harmonised Annex VI classification). This supports a 'suspected' reproductive hazard (h=2) but is not harmonised by the Commission. Mechanistic concern is class-based/theoretical (m=1) because salicylamide is a salicylate-related compound and salicylates are known to cross the placenta and be systemically available; direct mechanistic reproductive data for salicylamide are limited. Exposure from typical topical cosmetic use is expected to be low but measurable (evidence for dermal cosmetic exposure is limited), so e=1.
- salicylamide est-il sûr pendant l'allaitement ?
- Registrants have notified H361 (Repr.2) for salicylamide; salicylate metabolites are known to be excreted in human milk (class-based evidence), so a suspected hazard to nursing infants is appropriate (h=2) but this is based on registrant classification and read-across from salicylates rather than a harmonised/regulatory SCCS/CIR conclusion for salicylamide specifically. Systemic exposure after topical use is likely low but non-zero (e=1).
- salicylamide est-il sûr pour la peau de bébé ?
- Hazard (h) and mechanism (m) are kept the same as adult because there is no infant-specific evidence to upscore hazard or mechanism. Exposure (e) is increased by +1 for infants (e=2) per your rules because infant skin has higher surface‑area‑to‑weight and an immature barrier and salicylamide is a small molecule with some dermal absorption potential; therefore infant dermal exposure is moderately greater than adult.
- Comment VeriMom évalue-t-il salicylamide ?
- VeriMom évalue salicylamide à 27/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à salicylamide pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à salicylamide basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.