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임신 중 retinoic acid을 피해야 할까요? | VeriMom

All‑trans‑retinoic acid (tretinoin, CAS 302-79-4) has a harmonised reproductive hazard classification (Repr. 1A/1B, H360/D) in ECHA records and is prohibited in cosmetic products in the EU; oral retinoids are established human teratogens and retinoic acid acts through well‑characterised retinoid receptor (RAR/RXR) signalling that causes embryopathy. Topical absorption is measurable but generally low, so exposure from typical cosmetic topical use is low but not zero. (ECHA; FDA product literature; mechanistic and teratogenic literature).

ECHA regulatory hazard statements

  • H360D

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

retinoic acid은 임신 중 안전한가요?
All‑trans‑retinoic acid (tretinoin, CAS 302-79-4) has a harmonised reproductive hazard classification (Repr. 1A/1B, H360/D) in ECHA records and is prohibited in cosmetic products in the EU; oral retinoids are established human teratogens and retinoic acid acts through well‑characterised retinoid receptor (RAR/RXR) signalling that causes embryopathy. Topical absorption is measurable but generally low, so exposure from typical cosmetic topical use is low but not zero. (ECHA; FDA product literature; mechanistic and teratogenic literature).
retinoic acid은 모유 수유 중 안전한가요?
Direct data on excretion of topical tretinoin into human milk are limited/ inconclusive, but the compound is systemically active and a retinoid; because of systemic teratogenicity and potential for transfer, caution is advised. Systemic absorption from topical use is generally low, so breast‑milk exposure is likely low but not well‑quantified in humans. (ECHA; FDA/label information; limited pharmacokinetic studies).
retinoic acid은 아기 피부에 안전한가요?
Tretinoin is a known teratogenic retinoid with well‑defined RAR/RXR activity. Infant skin (0–3 yr) has higher surface‑area‑to‑weight and an immature barrier, so exposure score is increased by +1 relative to adults when topical absorption is measurable. Because tretinoin is prohibited in cosmetics in the EU and flagged as H360, it is not appropriate for use on infant skin. (ECHA; SCCS/CIR context; pediatric exposure considerations).
VeriMom은 retinoic acid을 어떻게 평가하나요?
VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 retinoic acid을 13/100 (높은 위험)로 평가합니다.
임신 중 retinoic acid 대체 안전 성분은?
유사한 기능을 가진 알려진 위험이 없는 대체 성분 목록을 확인하세요.

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의료 면책 조항

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