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¿Es retinoic acid seguro durante el embarazo?

All‑trans‑retinoic acid (tretinoin, CAS 302-79-4) has a harmonised reproductive hazard classification (Repr. 1A/1B, H360/D) in ECHA records and is prohibited in cosmetic products in the EU; oral retinoids are established human teratogens and retinoic acid acts through well‑characterised retinoid receptor (RAR/RXR) signalling that causes embryopathy. Topical absorption is measurable but generally low, so exposure from typical cosmetic topical use is low but not zero. (ECHA; FDA product literature; mechanistic and teratogenic literature).

Ingredientes
retinoic acid
RIESGO ALTO
13
/100
0

Alternativas seguras a retinoic acid en el embarazo | VeriMom

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Frequently asked questions

¿Es retinoic acid seguro durante el embarazo?
All‑trans‑retinoic acid (tretinoin, CAS 302-79-4) has a harmonised reproductive hazard classification (Repr. 1A/1B, H360/D) in ECHA records and is prohibited in cosmetic products in the EU; oral retinoids are established human teratogens and retinoic acid acts through well‑characterised retinoid receptor (RAR/RXR) signalling that causes embryopathy. Topical absorption is measurable but generally low, so exposure from typical cosmetic topical use is low but not zero. (ECHA; FDA product literature; mechanistic and teratogenic literature).
¿Es retinoic acid seguro durante la lactancia?
Direct data on excretion of topical tretinoin into human milk are limited/ inconclusive, but the compound is systemically active and a retinoid; because of systemic teratogenicity and potential for transfer, caution is advised. Systemic absorption from topical use is generally low, so breast‑milk exposure is likely low but not well‑quantified in humans. (ECHA; FDA/label information; limited pharmacokinetic studies).
¿Es retinoic acid seguro para la piel del bebé?
Tretinoin is a known teratogenic retinoid with well‑defined RAR/RXR activity. Infant skin (0–3 yr) has higher surface‑area‑to‑weight and an immature barrier, so exposure score is increased by +1 relative to adults when topical absorption is measurable. Because tretinoin is prohibited in cosmetics in the EU and flagged as H360, it is not appropriate for use on infant skin. (ECHA; SCCS/CIR context; pediatric exposure considerations).
¿Cómo puntúa VeriMom a retinoic acid?
VeriMom puntúa retinoic acid en 13/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
¿Cuáles son las alternativas seguras a retinoic acid en el embarazo?
Consulta nuestra lista de alternativas seguras a retinoic acid según función similar y clasificación sin riesgos conocidos.

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Aviso Médico

Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.

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