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HIGH RISK

Should I Avoid propylene glycol diundecanoate During Pregnancy? | VeriMom

Reviewed by · Last reviewed

ECHA regulatory hazard statements

  • H361

What to use instead

Pregnancy-safe ingredients that serve a similar function:

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Sources & references

Authoritative references used to score this ingredient.

Pregnancy-Safe Alternatives to propylene glycol diundecanoate | VeriMom

IngredientsPregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated

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FAQ

Is propylene glycol diundecanoate safe during pregnancy?
No developmental/reproductive (DART) studies for propylene glycol diundecanoate were identified and the Cosmetic Ingredient Review (CIR) group reviews of propylene glycol/PPG derivatives found insufficient DART data and concluded PEG/PPG‑type derivatives are 'safe as used' in cosmetics. No harmonised ECHA reproductive classification (e.g., H360/H361 harmonised classification) was found for CAS 68227-47-4. ([cir-safety.org](https://www.cir-safety.org/sites/default/files/pegpge122016rep.pdf))
Is propylene glycol diundecanoate safe while breastfeeding?
No human or animal data indicating reproductive or lactation-specific toxicity of propylene glycol diundecanoate were identified. No harmonised CLP classification for reproductive toxicity was located; therefore, under the stated scoring rules the default is 0. CIR and ingredient listings provide no contrary evidence. ([cir-safety.org](https://www.cir-safety.org/sites/default/files/pegpge122016rep.pdf))
Is propylene glycol diundecanoate safe for baby skin?
No infant-specific hazard or mechanism data found. The chemical is a very lipophilic diester (estimated log P ~9.7, very low water solubility) suggesting low systemic absorption after topical use in adults; however, because infant skin barrier immaturity can increase percutaneous uptake for some ingredients and this compound is not proven to be entirely non-absorbed, exposure score for 0–3 yr is increased by +1 versus adult. No DART or infant-specific studies were located. ([chemicalbook.com](https://www.chemicalbook.com/ChemicalProductProperty_EN_CB7888814.htm?utm_source=openai))
How does VeriMom score propylene glycol diundecanoate?
VeriMom scores propylene glycol diundecanoate at 39/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to propylene glycol diundecanoate?
See our curated list of pregnancy-safe alternatives to propylene glycol diundecanoate based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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