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HIGH RISK

Should I Avoid peg-25 oleamine During Pregnancy? | VeriMom

Reviewed by · Last reviewed

ECHA regulatory hazard statements

  • H361

What to use instead

Pregnancy-safe ingredients that serve a similar function:

Pregnancy-safe products to use instead

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Sources & references

Authoritative references used to score this ingredient.

Pregnancy-Safe Alternatives to peg-25 oleamine | VeriMom

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FAQ

Is peg-25 oleamine safe during pregnancy?
No EU harmonised CLH (H360/H361) for PEG‑25 oleamine was identified; CIR (Cosmetic Ingredient Review) assessed the PEG‑cocamine/oleamine family and concluded the group (including PEG‑25 oleamine) is ‘‘safe in cosmetics in the present practices of use and concentration when formulated to be non‑irritating’’ while noting reproductive/developmental effects for some analogs at high oral doses in animals. Given the class/structural relationship to alkyl ethoxylated amines and the analog oral DART findings, a structural/class‑based caution is appropriate (h=1, m=1). Topical cosmetic exposure is expected to be low but measurable (e=1). Sources: CIR review, PubChem/ECHA product listings, EWG summary. ([cir-safety.org](https://www.cir-safety.org/sites/default/files/pgcoca072015_FAR.pdf))
Is peg-25 oleamine safe while breastfeeding?
No specific lactation or milk‑transfer studies for PEG‑25 oleamine were found. By analogy to PEG‑amine class members (no specific DART via dermal exposure) and low expected systemic absorption from cosmetic topical use, hazard remains class/structure‑based (h=1) with theoretical mechanism only (m=1). Breastmilk exposure from topical use is likely low but measurable (e=1). ([cir-safety.org](https://www.cir-safety.org/sites/default/files/pgcoca072015_FAR.pdf))
Is peg-25 oleamine safe for baby skin?
CIR reviewed PEG‑oleamine series and found the class acceptable ‘‘as used’’ when non‑irritating; no infant‑specific studies for 0–3‑year skin were located. Following your scoring rules, because dermal absorption is plausible (measurable) for PEG‑type ethoxylates, exposure for baby skin is increased by +1 (adult e=1 → baby e=2). Hazard and mechanism remain class/structural (h=1, m=1) absent direct infant data. Formulations causing irritation should be avoided for infant skin. ([cir-safety.org](https://www.cir-safety.org/sites/default/files/pgcoca072015_FAR.pdf))
How does VeriMom score peg-25 oleamine?
VeriMom scores peg-25 oleamine at 27/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to peg-25 oleamine?
See our curated list of pregnancy-safe alternatives to peg-25 oleamine based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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