Should I Avoid p-tert-butyl-alpha-methylhydrocinnamal /methylanthranilate schiff base During Pregnancy? | VeriMom
No evidence of a harmonised CLP reproductive classification, no listing on EU Annex II/III, and I found no SCCS or CIR safety assessment identifying reproductive hazard for this specific Schiff‑base (sources show it as a fragrance ingredient/Schiff base, CAS 91‑51‑0). Regulatory and industry databases list it as a fragrance/Schiff base (The Good Scents Company, perfumery suppliers) but do not provide harmonised H360/H361 assignment. Given absence of harmonised CMR classification or peer‑reviewed reproductive/developmental animal data specific to this substance, hazard is scored 0. Exposure scored 1 because it is a typical small, lipophilic fragrance ingredient with potential low but measurable dermal absorption in cosmetic use. (Sources: The Good Scents Company; product/INCI listings; perfumery suppliers.).
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Is p-tert-butyl-alpha-methylhydrocinnamal /methylanthranilate schiff base safe during pregnancy?
- No evidence of a harmonised CLP reproductive classification, no listing on EU Annex II/III, and I found no SCCS or CIR safety assessment identifying reproductive hazard for this specific Schiff‑base (sources show it as a fragrance ingredient/Schiff base, CAS 91‑51‑0). Regulatory and industry databases list it as a fragrance/Schiff base (The Good Scents Company, perfumery suppliers) but do not provide harmonised H360/H361 assignment. Given absence of harmonised CMR classification or peer‑reviewed reproductive/developmental animal data specific to this substance, hazard is scored 0. Exposure scored 1 because it is a typical small, lipophilic fragrance ingredient with potential low but measurable dermal absorption in cosmetic use. (Sources: The Good Scents Company; product/INCI listings; perfumery suppliers.).
- Is p-tert-butyl-alpha-methylhydrocinnamal /methylanthranilate schiff base safe while breastfeeding?
- Same rationale as pregnancy: no harmonised CMR classification or SCCS/CIR reproductive/breastfeeding warnings specific to this Schiff base. Dermal exposure from cosmetics could be low but measurable; therefore exposure scored 1. No evidence found that the ingredient is known to concentrate in milk or to have demonstrated transfer to breastmilk.
- Is p-tert-butyl-alpha-methylhydrocinnamal /methylanthranilate schiff base safe for baby skin?
- No infant‑specific toxicology or harmonised reproductive classification found. Per scoring rules, infant exposure is increased by +1 because the ingredient has measurable dermal absorption as a fragrance component; infant exposure therefore scored 2. No data found showing infant‑specific hazards or mechanisms.
- How does VeriMom score p-tert-butyl-alpha-methylhydrocinnamal /methylanthranilate schiff base?
- VeriMom scores p-tert-butyl-alpha-methylhydrocinnamal /methylanthranilate schiff base at 33/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to p-tert-butyl-alpha-methylhydrocinnamal /methylanthranilate schiff base?
- See our curated list of pregnancy-safe alternatives to p-tert-butyl-alpha-methylhydrocinnamal /methylanthranilate schiff base based on similar function and a no-known-risks safety band.
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Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.