VeriMomShould I Avoid oxyquinoline During Pregnancy? | VeriMom
Reviewed by VeriMom Editorial Team · Last reviewed
ECHA regulatory hazard statements
- •H360D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
Pregnancy-safe products to use instead
Products built around the safer ingredients above, scored "no known risks" or "low risk".
Sources & references
Authoritative references used to score this ingredient.
Pregnancy-Safe Alternatives to oxyquinoline | VeriMom
Ingredients — Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
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FAQ
- Is oxyquinoline safe during pregnancy?
- Quinolin-8-ol (oxyquinoline, CAS 148-24-3) has an EU harmonised classification as a reproductive toxicant (Repr. 1B — H360D: “may damage the unborn child”), which by your scoring rules requires h=3. Mechanistic data linking a specific reproductive pathway are limited (mutagenicity was reported in some assays but no well‑characterised developmental mechanism), so m is scored 1 (theoretical/limited). For typical topical cosmetic use (used at ≤1% in formulations per CIR), dermal uptake is plausible but not high, so exposure (e) for pregnancy is scored 1 (low but measurable). (Sources: ECHA/EUR‑Lex harmonised classification; CIR safety assessment.).
- Is oxyquinoline safe while breastfeeding?
- Because the substance has a harmonised Repr.1B/H360D classification (systemic reproductive hazard), the hazard to nursing is scored h=3 under your rules. There is no clear, well‑established mechanism specific to lactational transfer (m=1). Dermal cosmetic use gives low but potentially measurable systemic exposure (e=1), so transfer into milk cannot be excluded at trace levels; no robust human milk data were found in the reviewed sources.
- Is oxyquinoline safe for baby skin?
- Do not increase hazard or mechanism absent infant‑specific data, so h=3 and m=1 as above. Because infant skin has higher permeability and surface‑area‑to‑weight, exposure score is increased by +1 from adult (adult e=1 → infant e=2), meaning moderate concern for systemic uptake from topical application to infant skin. No infant‑specific toxicokinetic or outcome studies were identified.
- How does VeriMom score oxyquinoline?
- VeriMom scores oxyquinoline at 27/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to oxyquinoline?
- See our curated list of pregnancy-safe alternatives to oxyquinoline based on similar function and a no-known-risks safety band.
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Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.