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임신 중 methoxyethanol을 피해야 할까요? | VeriMom

2‑Methoxyethanol (CAS 109‑86‑4, EGME) has a harmonised EU classification for reproductive toxicity (Repr. 1B / H360FD) and multiple animal studies (rats, mice) showing fetal/developmental effects and teratogenicity; it is metabolised to methoxyacetic acid which mediates these effects. (ECHA substance & CLP background; rat developmental studies). Sources: ECHA substance profile and CLP background (harmonised Repr.1B/H360FD) and peer‑reviewed animal studies (PubMed). (https://echa.europa.eu/substance-information/-/substanceinfo/100.003.377; https://echa.europa.eu/documents/10162/aade66ad-5922-8029-d9a5-ea38c1bc25f3; https://pubmed.ncbi.nlm.nih.gov/2755424/).

ECHA regulatory hazard statements

  • H360FD

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

methoxyethanol은 임신 중 안전한가요?
2‑Methoxyethanol (CAS 109‑86‑4, EGME) has a harmonised EU classification for reproductive toxicity (Repr. 1B / H360FD) and multiple animal studies (rats, mice) showing fetal/developmental effects and teratogenicity; it is metabolised to methoxyacetic acid which mediates these effects. (ECHA substance & CLP background; rat developmental studies). Sources: ECHA substance profile and CLP background (harmonised Repr.1B/H360FD) and peer‑reviewed animal studies (PubMed). (https://echa.europa.eu/substance-information/-/substanceinfo/100.003.377; https://echa.europa.eu/documents/10162/aade66ad-5922-8029-d9a5-ea38c1bc25f3; https://pubmed.ncbi.nlm.nih.gov/2755424/).
methoxyethanol은 모유 수유 중 안전한가요?
The hazard to reproduction/lactation is supported by harmonised classification and animal data; metabolism to methoxyacetic acid is a demonstrated mechanism. Systemic absorption is required for milk transfer; for cosmetic topical use systemic exposure is expected to be low but measurable, so breastfeeding exposure is possible if systemic absorption occurs (regulatory/animal data indicate systemic toxicity after inhalation/oral/dermal routes). (ECHA; IRIS/occupational reviews). (https://echa.europa.eu/substance-information/-/substanceinfo/100.003.377; https://cfpub.epa.gov/ncea/iris/iris_documents/documents/subst/0525_summary.pdf; https://www.cdc.gov/niosh/docs/83-112/default.html).
methoxyethanol은 아기 피부에 안전한가요?
Hazard and mechanism are the same (harmonised reprotoxic classification and demonstrated metabolite‑mediated effects). Dermal/topical exposure on infant skin results in higher exposure ranking than adults because infant skin has higher surface‑area‑to‑weight and an immature barrier; therefore exposure score is increased by +1 (adult e=1 → baby e=2). Regulatory/animal evidence supports systemic developmental toxicity; avoid use on infant skin. (ECHA; occupational reviews; IRIS). (https://echa.europa.eu/substance-information/-/substanceinfo/100.003.377; https://www.cdc.gov/niosh/docs/83-112/default.html; https://cfpub.epa.gov/ncea/iris/iris_documents/documents/subst/0525_summary.pdf).
VeriMom은 methoxyethanol을 어떻게 평가하나요?
VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 methoxyethanol을 20/100 (높은 위험)로 평가합니다.
임신 중 methoxyethanol 대체 안전 성분은?
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