VeriMomVeriMom
HIGH RISK

Should I Avoid ibuprofen During Pregnancy? | VeriMom

Reviewed by · Last reviewed

ECHA regulatory hazard statements

  • H360
  • H361
  • H362

Products containing ibuprofen — check your shelf

These products list ibuprofen on their INCI. If one is in your routine, consider swapping it during pregnancy.

What to use instead

Pregnancy-safe ingredients that serve a similar function:

Pregnancy-safe products to use instead

Products built around the safer ingredients above, scored "no known risks" or "low risk".

Sources & references

Authoritative references used to score this ingredient.

Pregnancy-Safe Alternatives to ibuprofen | VeriMom

IngredientsPregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated

See also

FAQ

Is ibuprofen safe during pregnancy?
Ibuprofen (CAS 15687-27-1) is an NSAID with human/animal evidence of adverse fetal effects (fetal renal dysfunction/oligohydramnios and premature ductus arteriosus closure) prompting an FDA warning to avoid NSAID use at ≈20 weeks gestation and later; this supports a 'suspected' reproductive hazard (h=2). The mechanism is demonstrated (prostaglandin inhibition → fetal renal/ductus arteriosus effects), so m=2. Topical/cosmetic use yields low but measurable systemic exposure vs oral use, so exposure for topical cosmetic use is low (e=1). Sources: FDA, MotherToBaby/NCBI, ECHA substance information.
Is ibuprofen safe while breastfeeding?
Available clinical guidance and reviews indicate very low transfer of ibuprofen into human milk and no documented infant harm for usual maternal doses; therefore no reproductive/breastfeeding hazard is indicated (h=0, m=0). Milk transfer is measurable but low, so e=1. Sources: MotherToBaby (NCBI), NHS Specialist Pharmacy Service; clinical references note ibuprofen is generally compatible with breastfeeding.
Is ibuprofen safe for baby skin?
Hazard (h=2) is carried over because systemic reproductive/toxicity evidence for ibuprofen exists (see pregnancy summary). Per instructions, infant-specific hazard or mechanism were not found so h and m are not increased beyond adult evidence (m=2). Topical exposure for infants is increased relative to adults (immature barrier and higher surface-area-to-weight) so exposure is raised by +1 (adult e=1 → baby e=2). No infant-specific studies were found showing different hazard; precautionary higher exposure score applied.
How does VeriMom score ibuprofen?
VeriMom scores ibuprofen at 20/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to ibuprofen?
See our curated list of pregnancy-safe alternatives to ibuprofen based on similar function and a no-known-risks safety band.

Check every label in 2 seconds

Get VeriMom free — scan any product and see the pregnancy safety score instantly.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

Get the full experience in the VeriMom app