¿Debo evitar epichlorohydrin durante el embarazo? | VeriMom
Animal developmental and reproductive toxicity studies (one-generation and developmental studies) report adverse effects; ECHA registration dossier and EPA summaries document these findings and some C&L notifications list H361 (suspected reproductive toxicant). There is mechanistic evidence that epichlorohydrin is a reactive epoxide (genotoxic/alkylating) which plausibly underlies developmental/reproductive toxicity. Topical cosmetic exposure would be low but measurable; epichlorohydrin has a skin penetration (NIOSH skin notation) so systemic exposure is possible if used on skin. (Sources: ECHA registration dossier; PubMed study; EPA summary; NIOSH/NIOSH PEL page).
ECHA regulatory hazard statements
- •H350
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- ¿Es epichlorohydrin seguro durante el embarazo?
- Animal developmental and reproductive toxicity studies (one-generation and developmental studies) report adverse effects; ECHA registration dossier and EPA summaries document these findings and some C&L notifications list H361 (suspected reproductive toxicant). There is mechanistic evidence that epichlorohydrin is a reactive epoxide (genotoxic/alkylating) which plausibly underlies developmental/reproductive toxicity. Topical cosmetic exposure would be low but measurable; epichlorohydrin has a skin penetration (NIOSH skin notation) so systemic exposure is possible if used on skin. (Sources: ECHA registration dossier; PubMed study; EPA summary; NIOSH/NIOSH PEL page).
- ¿Es epichlorohydrin seguro durante la lactancia?
- Same rationale as for pregnancy: animal data and regulatory dossiers indicate reproductive/developmental hazard (H361 notifications). Mechanistic genotoxic/reactive epoxide activity supports potential for systemic harm. Dermal absorption is possible so measurable maternal systemic exposure (and therefore theoretical transfer to breastmilk) cannot be excluded, though direct lactation-specific data are unavailable.
- ¿Es epichlorohydrin seguro para la piel del bebé?
- Hazard and mechanism same as adults (animal reproductive/developmental effects; reactive epoxide chemistry). Because epichlorohydrin is skin-penetrant (NIOSH skin notation) and infant skin has higher surface-area-to-weight and immature barrier, exposure score is increased by +1 (adult e=1 → infant e=2). There are no infant-specific safety studies identified.
- ¿Cómo puntúa VeriMom a epichlorohydrin?
- VeriMom puntúa epichlorohydrin en 20/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a epichlorohydrin en el embarazo?
- Consulta nuestra lista de alternativas seguras a epichlorohydrin según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.