VeriMomSollte ich clotrimazole in der Schwangerschaft meiden? | VeriMom
Clotrimazole is listed with a harmonised CLP classification of H361 (suspected of damaging fertility or the unborn child) on ECHA, which supports a ‘suspected’ reproductive hazard (h=2). A recent peer‑reviewed rat study showed that systemic exposure to clotrimazole altered maternal and fetal steroid hormone profiles via CYP/steroidogenesis inhibition (demonstrated mechanism → m=2). For typical topical/vaginal cosmetic/OTC use systemic absorption is minimal but measurable, so exposure from topical cosmetic use is rated low (e=1). Sources: ECHA harmonised classification and PubMed study, plus product labeling on animal effects.
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Ist clotrimazole in der Schwangerschaft sicher?
- Clotrimazole is listed with a harmonised CLP classification of H361 (suspected of damaging fertility or the unborn child) on ECHA, which supports a ‘suspected’ reproductive hazard (h=2). A recent peer‑reviewed rat study showed that systemic exposure to clotrimazole altered maternal and fetal steroid hormone profiles via CYP/steroidogenesis inhibition (demonstrated mechanism → m=2). For typical topical/vaginal cosmetic/OTC use systemic absorption is minimal but measurable, so exposure from topical cosmetic use is rated low (e=1). Sources: ECHA harmonised classification and PubMed study, plus product labeling on animal effects.
- Ist clotrimazole während des Stillens sicher?
- Harmonised H361 classification and animal data (CYP inhibition and steroid changes) provide evidence for a suspected reproductive/developmental hazard (h=2) and a demonstrated mechanistic effect (m=2). Topical use shows minimal but measurable systemic absorption and is therefore given low exposure (e=1); breastfeeding guidance notes limited systemic exposure with topical use but advises use only if benefits outweigh risks in some labels.
- Ist clotrimazole sicher für Babyhaut?
- Hazard (h=2) remains based on harmonised H361 and animal evidence; mechanism (m=2) is the same (CYP/steroidogenesis effects demonstrated in animals). Exposure is increased by one band for infants because infant skin has higher absorption — adult topical e=1 → baby e=2 (measurable/moderate exposure potential for 0–3 yr). There is limited infant‑specific reproductive/toxicity data; topical clotrimazole has been used in infants in clinical studies but systemic safety data are limited.
- Wie bewertet VeriMom clotrimazole?
- VeriMom bewertet clotrimazole mit 20/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu clotrimazole?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu clotrimazole basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.