VeriMomHIGH RISK
Should I Avoid acetyl benzoyloxy prasterone During Pregnancy? | VeriMom
Reviewed by VeriMom Editorial Team · Last reviewed
What to use instead
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Sources & references
Authoritative references used to score this ingredient.
Pregnancy-Safe Alternatives to acetyl benzoyloxy prasterone | VeriMom
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See also
FAQ
- Is acetyl benzoyloxy prasterone safe during pregnancy?
- No EU Annex II/III ban or harmonised CLP classification was found for this CAS; however the compound is a prasterone (DHEA) ester and prasterone has androgen/estrogen activity in humans (medicinal use). Steroidal hormonal activity implies suspected reproductive/developmental hazard for pregnancy (calibration: demonstrated endocrine activity → h=2). There are clinical/peer-reviewed sources describing prasterone as an active steroid. No harmonised H360/H361 or Annex II listing was found for this specific derivative. (Sources: PubMed prasterone review; INCI/Gazzetta INCI listing.)
- Is acetyl benzoyloxy prasterone safe while breastfeeding?
- Same rationale as pregnancy: the derivative can be expected to act (or be metabolised to) a steroid hormone (prasterone) with potential to reach systemic circulation; steroids may be transferred into breastmilk and affect nursing infants—this produces a suspected hazard in breastfeeding (h=2). No direct breastfeeding-specific studies on this derivative were located. (Sources: prasterone clinical literature; INCI lists.)
- Is acetyl benzoyloxy prasterone safe for baby skin?
- Hazard and mechanism scores reflect the steroidal parent (prasterone) activity (suspected endocrine/reproductive hazard). Exposure score is increased for infant skin: topical steroidal molecules or esters that are measurably absorbable in adults are likely to have higher per-bodyweight exposure in infants with immature barrier function—so adult e=2 (moderate absorption expected for a lipophilic steroid-ester), infant e elevated to 3 per instructions. No infant-specific dermal studies for this compound were found. (Sources: INCI / cosmetic ingredient databases; prasterone clinical literature.)
- How does VeriMom score acetyl benzoyloxy prasterone?
- VeriMom scores acetyl benzoyloxy prasterone at 33/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to acetyl benzoyloxy prasterone?
- See our curated list of pregnancy-safe alternatives to acetyl benzoyloxy prasterone based on similar function and a no-known-risks safety band.
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Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.