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HIGH RISK

Should I Avoid 1,4-butanediol dimethacrylate During Pregnancy? | VeriMom

Reviewed by · Last reviewed

ECHA regulatory hazard statements

  • H317

What to use instead

Pregnancy-safe ingredients that serve a similar function:

Pregnancy-safe products to use instead

Products built around the safer ingredients above, scored "no known risks" or "low risk".

Sources & references

Authoritative references used to score this ingredient.

Pregnancy-Safe Alternatives to 1,4-butanediol dimethacrylate | VeriMom

IngredientsPregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated

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FAQ

Is 1,4-butanediol dimethacrylate safe during pregnancy?
No harmonised reproductive classification in ECHA Annex VI. The only legally binding classification listed is H317 (skin sensitiser) for tetramethylene dimethacrylate (ECHA Annex VI). PubChem aggregate notifications include a repro flag (H361) but this is not harmonised and per your instructions self/aggregate notifications do not warrant h>0. No SCCS or CIR reproductive safety assessment located in provided data.
Is 1,4-butanediol dimethacrylate safe while breastfeeding?
No authoritative evidence (harmonised CLP, SCCS, CIR, or peer-reviewed reproductive/lactation studies) indicating effects on lactation or nursing infants. Only established hazard is skin sensitisation (H317).
Is 1,4-butanediol dimethacrylate safe for baby skin?
No evidence of a reproductive hazard specific to infants. Exposure score increased by +1 for baby skin because although no firm data on dermal systemic absorption were provided, monomeric methacrylates are not completely non-absorbable and infant skin has higher absorption potential; therefore a precautionary small increase in exposure is applied. The compound’s harmonised classification is for skin sensitisation (H317), not reproductive toxicity (ECHA Annex VI).
How does VeriMom score 1,4-butanediol dimethacrylate?
VeriMom scores 1,4-butanediol dimethacrylate at 39/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to 1,4-butanediol dimethacrylate?
See our curated list of pregnancy-safe alternatives to 1,4-butanediol dimethacrylate based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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