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Is soluble fibroin safe during pregnancy?

Reviewed by · Last reviewed

Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
soluble fibroin
NO KNOWN RISKS
100
/100
0

Pregnancy-safe products containing soluble fibroin

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Authoritative references used to score this ingredient.

Frequently asked questions

Is soluble fibroin safe during pregnancy?
Soluble fibroin (silk fibroin/hydrolyzed silk protein) is a high‑molecular‑weight protein/peptide used as a cosmetic functional ingredient. No harmonised reproductive hazard classification (ECHA Annex VI), no SCCS/CIR reproductive safety flags, and peer‑reviewed literature describes biocompatibility rather than teratogenicity, so no evidence of reproductive hazard or mechanism and systemic exposure from topical cosmetic use is expected to be negligible.
Is soluble fibroin safe while breastfeeding?
Same rationale as pregnancy: no regulatory harmonised classification or published data indicating reproductive or lactation risk; intact protein/large peptides have low dermal bioavailability in cosmetics, so maternal systemic exposure (and thus transfer into milk) is expected to be negligible.
Is soluble fibroin safe for baby skin?
No evidence of developmental toxicity specific to infants. However, because soluble fibroin is a protein/peptide with at least potential for limited percutaneous uptake of small peptides and infant skin has higher permeability, exposure score is increased by +1 for 0–3 yr skin versus adults; no data indicate increased hazard or specific mechanism in infants.
How does VeriMom score soluble fibroin?
VeriMom scores soluble fibroin at 100/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to soluble fibroin?
See our curated list of pregnancy-safe alternatives to soluble fibroin based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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