Is propylene glycol oleate safe during pregnancy?

Pregnancy-Safe Alternatives to propylene glycol oleate | VeriMom

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See also

• Is propylene glycol oleate safe for babies?
• Should I avoid propylene glycol oleate during pregnancy?
• What are pregnancy-safe alternatives to propylene glycol oleate?

Frequently asked questions

Is propylene glycol oleate safe during pregnancy?

No EU harmonised reproductive hazard or cosmetic ban/restriction identified for propylene glycol monooleate (CAS 1330-80-9); the ECHA substance infocard lists uses in cosmetics but no CLH (harmonised) reproductive classification. The Cosmetic Ingredient Review (CIR) safety assessment of propylene glycol esters (which includes propylene glycol oleate) concluded these esters are safe for cosmetic use as formulated — no human teratogenic or developmental signal was identified in those reviews. Based on this hierarchy (no Annex II/III listing, no harmonised H360/H361 CMR classification, and a CIR safety conclusion), hazard (h) and mechanism (m) scores are 0. Adult topical exposure is low but measurable from cosmetic use, so exposure (e) is 1. (Sources: ECHA substance infocard; CIR safety review; EWG ingredient entry.)

Is propylene glycol oleate safe while breastfeeding?

Same rationale as pregnancy: no harmonised reproductive or lactation-specific hazard identified and CIR concluded safety for cosmetic use. Topical exposure during breastfeeding is low but measurable (e=1); no mechanism indicating transfer in milk was found in the available reviews. (Sources: CIR; ECHA; EWG.)

Is propylene glycol oleate safe for baby skin?

No direct evidence of developmental or infant-specific reproductive toxicity or harmonised CMR classification. However, because infant skin (0–3 yr) has a less mature barrier and higher surface-area-to-weight, measurable dermal absorption for an oil‑type ester supports increasing exposure score by +1 for baby skin (adult e=1 → baby e=2). There is no infant‑specific data that would change hazard (h) or mechanism (m). (Sources: CIR review; ECHA substance information.)

How does VeriMom score propylene glycol oleate?

VeriMom scores propylene glycol oleate at 33/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.

What are pregnancy-safe alternatives to propylene glycol oleate?

See our curated list of pregnancy-safe alternatives to propylene glycol oleate based on similar function and a no-known-risks safety band.