Is polyquaternium-51 safe during pregnancy?
Reviewed by VeriMom Editorial Team · Last reviewed
Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
polyquaternium-51
NO KNOWN RISKS100
/100
0









Pregnancy-safe products containing polyquaternium-51

Numbuzin
numbuzin No.9 NAD+ BIO Lifting-sil Essence - 30ml (1ea) & NAD+ Collagen Under Eye Patches - 2ea Set
99/100

numbuzin No.4 Icy Soothing Sheet Mask - 27g*4ea
99/100

BCL
BCL Cleansing Research Wash Cleansing Acne - /120g (4ea) Set
99/100

BCL
BCL AHA By Cleansing Research Lavage
99/100

Rohto Mentholatum AD Lotion - 200g
99/100

Mandom
Mandom Barrier Repair Beauty Serum Mask - Brightening - 4pcs
99/100

OSSOLA Skincare
OSSOLA Skincare Melon Milk Mattifying Primer
99/100

BCL
BCL Cleansing Research 3-in-1 Wash Cleansing C - 120g (2ea) Set
99/100

BCL
BCL Cleansing Research Wash Cleansing Acne - /120g (10ea) Set
99/100

Numbuzin
numbuzin Dry Skincare Set A
99/100
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Sources & references
Authoritative references used to score this ingredient.
Frequently asked questions
- Is polyquaternium-51 safe during pregnancy?
- No harmonised CLP reproductive classifications or SCCS/CIR safety findings were identified for polyquaternium‑51; it is a high‑molecular‑weight quaternary ammonium polymer with no published reproductive toxicity or teratogenicity data in the regulatory/authoritative sources checked (ECHA Annex VI, PubChem, CosIng). Polymers of this type are generally poorly absorbed dermally, so topical maternal exposure is expected to be negligible.
- Is polyquaternium-51 safe while breastfeeding?
- No evidence of reproductive or lactation-specific toxicity or systemic maternal effects was identified in authoritative sources (no harmonised CLP, no SCCS/CIR assessment indicating hazard). Given the polymeric high‑MW nature and expected minimal dermal absorption, transfer into breast milk is unlikely and exposure to nursing infants from topical maternal use is expected to be negligible.
- Is polyquaternium-51 safe for baby skin?
- No infant‑specific reproductive or developmental hazards were identified. Polyquaternium‑51 is a high‑molecular‑weight polymer with low expected systemic absorption; however, immature infant skin has higher permeability, so dermal exposure for babies (0–3 yr) is considered low but measurable (adult exposure scored 0 → infant exposure scored +1). No studies were found that demonstrate placental transfer, endocrine activity, or infant toxicity.
- How does VeriMom score polyquaternium-51?
- VeriMom scores polyquaternium-51 at 100/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to polyquaternium-51?
- See our curated list of pregnancy-safe alternatives to polyquaternium-51 based on similar function and a no-known-risks safety band.
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Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.