VeriMomБезопасен ли polybutylene glycol/mdi copolymer при беременности?
No harmonised reproductive classification (ECHA Annex VI) or CIR/SCCS opinion for 'polybutylene glycol/MDI copolymer' was identified. Regulatory concerns for MDI relate mainly to sensitisation and acute toxicity; polymeric MDI products are generally considered distinct from monomeric MDI with much lower bioavailability. In absence of reproductive/toxicology data or harmonised H360/H361 classifications for this specific polymer, default scoring is 0. Sources consulted: ECHA Annex VI (harmonised CLP), PubChem (MDI hazard profile), ECHA registration dossiers/CosIng (no reproductive classification for polymer).
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Frequently asked questions
- Безопасен ли polybutylene glycol/mdi copolymer при беременности?
- No harmonised reproductive classification (ECHA Annex VI) or CIR/SCCS opinion for 'polybutylene glycol/MDI copolymer' was identified. Regulatory concerns for MDI relate mainly to sensitisation and acute toxicity; polymeric MDI products are generally considered distinct from monomeric MDI with much lower bioavailability. In absence of reproductive/toxicology data or harmonised H360/H361 classifications for this specific polymer, default scoring is 0. Sources consulted: ECHA Annex VI (harmonised CLP), PubChem (MDI hazard profile), ECHA registration dossiers/CosIng (no reproductive classification for polymer).
- Безопасен ли polybutylene glycol/mdi copolymer при грудном вскармливании?
- Same rationale as for pregnancy: no specific reproductive or lactation hazard identified for the polymer. Potential risk would stem from residual monomer (MDI) which is primarily a local irritant/sensitiser; no evidence that the polymer itself transfers into milk or causes systemic reproductive toxicity. No CIR/SCCS or harmonised CLP reproductive flags for the polymer were found.
- Безопасен ли polybutylene glycol/mdi copolymer для кожи малыша?
- Hazard and mechanism remain 0 for the polymer (no reproductive/teratogenic evidence). Exposure score increased by +1 for infants because infant skin has higher permeability and surface area:weight, so if any low‑MW residual MDI/oligomers are present they could have measurable absorption. However, the intact high‑MW polymer itself is expected to have negligible dermal absorption. Key concern is residual free MDI rather than the polymer.
- Как VeriMom оценивает polybutylene glycol/mdi copolymer?
- VeriMom оценивает polybutylene glycol/mdi copolymer в 100/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы polybutylene glycol/mdi copolymer при беременности?
- См. наш список безопасных альтернатив polybutylene glycol/mdi copolymer с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.