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Is poloxamer 188 safe during pregnancy?

Reviewed by · Last reviewed

Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
poloxamer 188
NO KNOWN RISKS
100
/100
0

Pregnancy-safe products containing poloxamer 188

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Authoritative references used to score this ingredient.

Frequently asked questions

Is poloxamer 188 safe during pregnancy?
The Cosmetic Ingredient Review (CIR) evaluated poloxamers (including poloxamer 188) and concluded they are safe as used in cosmetics; there is no harmonised CLP reproductive classification on the ECHA substance page and no human teratogenic or reproductive hazard (H360/H361) identified in authoritative reviews or regulatory listings. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/18830866/?utm_source=openai))
Is poloxamer 188 safe while breastfeeding?
No authoritative source (CIR/SCCS/harmonised CLP) identifies reproductive or lactation-specific hazards for poloxamer 188; available toxicology and safety reviews do not report effects on lactation or maternal reproductive organs at cosmetic use levels. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/18830866/?utm_source=openai))
Is poloxamer 188 safe for baby skin?
CIR’s safety assessment of poloxamers found them safe as used in cosmetics; no evidence of infant-specific reproductive hazard was located. Because poloxamer 188 is water-soluble and used topically (and not reported as completely non-absorbable), exposure for 0–3 yr skin is increased vs adults (immature barrier / higher SA:BW), so exposure (e) is scored 1 while hazard/mechanism remain 0 absent infant-specific adverse data. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/18830866/?utm_source=openai))
How does VeriMom score poloxamer 188?
VeriMom scores poloxamer 188 at 100/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to poloxamer 188?
See our curated list of pregnancy-safe alternatives to poloxamer 188 based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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