VeriMomoctoxynol-9 est-il sûr pendant la grossesse ?
CIR’s final/amended safety assessment concluded octoxynols (including octoxynol‑9) are safe as used in cosmetics and identified no harmonised reproductive hazard; a dedicated rat teratology study with intravaginal octoxynol‑9 reported no maternal or fetal developmental effects. However, in vitro and in vivo data show that octylphenol (the de‑ethoxylation product) is estrogenic — a mechanistic concern for the parent phenol exists but not demonstrated for octoxynol‑9 in pregnancy at cosmetic exposures. Skin absorption data in the safety assessment indicate low but measurable absorption from topical formulations, so exposure (e) is scored as 1 (low but measurable). Sources: CIR safety assessment; rat teratology study; review on 4‑tert‑octylphenol.
Pregnancy-safe products containing octoxynol-9
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Frequently asked questions
- octoxynol-9 est-il sûr pendant la grossesse ?
- CIR’s final/amended safety assessment concluded octoxynols (including octoxynol‑9) are safe as used in cosmetics and identified no harmonised reproductive hazard; a dedicated rat teratology study with intravaginal octoxynol‑9 reported no maternal or fetal developmental effects. However, in vitro and in vivo data show that octylphenol (the de‑ethoxylation product) is estrogenic — a mechanistic concern for the parent phenol exists but not demonstrated for octoxynol‑9 in pregnancy at cosmetic exposures. Skin absorption data in the safety assessment indicate low but measurable absorption from topical formulations, so exposure (e) is scored as 1 (low but measurable). Sources: CIR safety assessment; rat teratology study; review on 4‑tert‑octylphenol.
- octoxynol-9 est-il sûr pendant l'allaitement ?
- No authoritative safety assessment (CIR) or harmonised classification flags reproductive/teratogenic effects for octoxynol‑9 and clinical/breastfeeding specific adverse outcomes are not reported in the high‑priority literature. Lactation databases and older clinical reports on related spermicides (nonoxynol‑9) did not show infant harm; nevertheless, low systemic absorption is possible and theoretical transfer in milk cannot be entirely excluded, so exposure is scored as 1 (low but measurable).
- octoxynol-9 est-il sûr pour la peau de bébé ?
- CIR concluded octoxynols are safe as used but noted irritation concerns for some uses; skin absorption studies cited in the CIR/amended report indicate measurable absorption for octoxynols. Because infant skin (0–3 yr) has higher surface‑area‑to‑weight and an immature barrier, exposure is increased by +1 relative to adults (adult e=1 → baby e=2). There is no infant‑specific evidence demonstrating elevated hazard or a different mechanism in babies.
- Comment VeriMom évalue-t-il octoxynol-9 ?
- VeriMom évalue octoxynol-9 à 93/100 (pas de risques connus) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à octoxynol-9 pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à octoxynol-9 basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.