¿Es melia azadirachta (neem) leaf seguro durante el embarazo?
Animal studies report reproductive/antifertility effects from neem/Melia extracts (seed extracts inhibited folliculogenesis in rats; some neem leaf extracts produced altered fetal ossification at high oral doses), so this meets 'suspected' (h=2). Mechanistic evidence shows demonstrated effects on ovarian folliculogenesis/fertility in animals (m=2). For topical cosmetic use systemic absorption is expected to be low but measurable, so exposure for typical adult topical use is low (e=1). Sources: animal reproductive studies and a maternal–fetal rat study. (PubMed: Roop et al. 2005; Ramalho et al. 2023; see sources list).
Alternativas seguras a melia azadirachta (neem) leaf en el embarazo | VeriMom
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Frequently asked questions
- ¿Es melia azadirachta (neem) leaf seguro durante el embarazo?
- Animal studies report reproductive/antifertility effects from neem/Melia extracts (seed extracts inhibited folliculogenesis in rats; some neem leaf extracts produced altered fetal ossification at high oral doses), so this meets 'suspected' (h=2). Mechanistic evidence shows demonstrated effects on ovarian folliculogenesis/fertility in animals (m=2). For topical cosmetic use systemic absorption is expected to be low but measurable, so exposure for typical adult topical use is low (e=1). Sources: animal reproductive studies and a maternal–fetal rat study. (PubMed: Roop et al. 2005; Ramalho et al. 2023; see sources list).
- ¿Es melia azadirachta (neem) leaf seguro durante la lactancia?
- Same hazard and mechanism considerations as pregnancy because animal data show effects on reproduction and development; for topical cosmetics maternal systemic exposure is likely low but measurable, so potential for excretion into milk is possible though not established (thus e=1).
- ¿Es melia azadirachta (neem) leaf seguro para la piel del bebé?
- No infant-specific toxicology demonstrating developmental/reproductive effects from topical exposure; therefore hazard is lowered to a precautionary class-based/structural concern (h=1) because botanical extracts can contain bioactive constituents. Mechanistic pregnancy-level endocrine evidence is from systemic/oral animal studies, not infant-skin specific (m=0). Exposure is increased by one category for baby skin (immature barrier/higher SA:BW) from the adult topical level (adult e=1 → baby e=2).
- ¿Cómo puntúa VeriMom a melia azadirachta (neem) leaf?
- VeriMom puntúa melia azadirachta (neem) leaf en 40/100 (riesgo medio) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a melia azadirachta (neem) leaf en el embarazo?
- Consulta nuestra lista de alternativas seguras a melia azadirachta (neem) leaf según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.