Безопасен ли glycyrrhiza glabra root water при беременности?
No EU Annex II/III restriction or harmonised CLP reproductive classification was identified; the Cosmetic Ingredient Review (CIR) concluded Glycyrrhiza-derived cosmetic ingredients are safe for topical use as used. However, peer‑reviewed human and animal literature links maternal licorice/glycyrrhizin exposure to reproductive/developmental outcomes (preterm delivery, altered child neuroendocrine/cognitive outcomes) via demonstrated inhibition of placental 11β‑HSD2, so a class/mechanistic concern exists though primarily for oral/high exposures and not supported by an EU harmonised hazard classification. Sources: CIR/CosmeticsInfo; PubMed epidemiology/mechanistic studies.
Pregnancy-safe products containing glycyrrhiza glabra root water
Безопасные альтернативы glycyrrhiza glabra root water при беременности | VeriMom
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Frequently asked questions
- Безопасен ли glycyrrhiza glabra root water при беременности?
- No EU Annex II/III restriction or harmonised CLP reproductive classification was identified; the Cosmetic Ingredient Review (CIR) concluded Glycyrrhiza-derived cosmetic ingredients are safe for topical use as used. However, peer‑reviewed human and animal literature links maternal licorice/glycyrrhizin exposure to reproductive/developmental outcomes (preterm delivery, altered child neuroendocrine/cognitive outcomes) via demonstrated inhibition of placental 11β‑HSD2, so a class/mechanistic concern exists though primarily for oral/high exposures and not supported by an EU harmonised hazard classification. Sources: CIR/CosmeticsInfo; PubMed epidemiology/mechanistic studies.
- Безопасен ли glycyrrhiza glabra root water при грудном вскармливании?
- Same rationale as pregnancy: no regulatory ban or harmonised CMR classification, CIR finds topical licorice ingredients safe as used, but glycyrrhizin/glycyrrhetinic acid have demonstrated endocrine activity (placental 11β‑HSD2 inhibition) and systemic effects after ingestion; breastfeeding concerns are theoretical at topical cosmetic exposures but mechanism is demonstrated for systemic exposures.
- Безопасен ли glycyrrhiza glabra root water для кожи малыша?
- Hazard and mechanism scores are unchanged (no infant‑specific hazard data), but exposure (e) is increased by +1 for infants because immature skin barrier and higher surface‑area‑to‑weight can raise absorption; no evidence found that topical cosmetic use of Glycyrrhiza glabra root water is specifically harmful to infant skin, and CIR concluded dermal penetration is low for typical cosmetic preparations.
- Как VeriMom оценивает glycyrrhiza glabra root water?
- VeriMom оценивает glycyrrhiza glabra root water в 60/100 (средний риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы glycyrrhiza glabra root water при беременности?
- См. наш список безопасных альтернатив glycyrrhiza glabra root water с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.
