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Is diazolidinyl urea safe during pregnancy?

Formaldehyde-releaser of the same class as DMDM hydantoin — slowly releases a Group 1 carcinogen. Common contact allergen. Listed on most pregnancy-skincare avoid lists.

Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
diazolidinyl urea
MEDIUM RISK
47
/100
0

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Pregnancy-Safe Alternatives to diazolidinyl urea | VeriMom

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Frequently asked questions

Is diazolidinyl urea safe during pregnancy?
Formaldehyde-releaser of the same class as DMDM hydantoin — slowly releases a Group 1 carcinogen. Common contact allergen. Listed on most pregnancy-skincare avoid lists.
Is diazolidinyl urea safe while breastfeeding?
Same hazard basis as pregnancy (no harmonised CMR classification; CIR & EU CosIng allow use up to 0.5%). Mechanistic concern is theoretical (formaldehyde release; in vitro cytotoxicity reported). Systemic exposure from normal topical cosmetic use is considered low but measurable, so transfer into breastmilk is plausible but not documented; therefore exposure scored low. Sources: CIR, CosIng (EU Regulation), PubMed study on in vitro effects, ECHA registration info.
Is diazolidinyl urea safe for baby skin?
Hazard and mechanistic scoring kept same as adult (no infant‑specific evidence of greater hazard). Exposure score increased by +1 for infants because immature skin and higher surface‑area‑to‑weight ratio increase absorption; topical use therefore gives moderate exposure potential. No infant dermal toxicokinetic or developmental studies specific to 0–3 yr were identified. Sources: EU CosIng (Annex V), CIR, in vitro studies (neural progenitor cytotoxicity), EWG summary.
How does VeriMom score diazolidinyl urea?
VeriMom scores diazolidinyl urea at 47/100 (medium risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to diazolidinyl urea?
See our curated list of pregnancy-safe alternatives to diazolidinyl urea based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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