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Is acetyl sh-pentapeptide-35 safe during pregnancy?

Reviewed by · Last reviewed

Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
acetyl sh-pentapeptide-35
NO KNOWN RISKS
100
/100
0

Pregnancy-safe products containing acetyl sh-pentapeptide-35

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Authoritative references used to score this ingredient.

Frequently asked questions

Is acetyl sh-pentapeptide-35 safe during pregnancy?
No harmonised CLP classification (ECHA Annex VI), no SCCS or CIR reproductive safety concerns located, and no peer-reviewed reproductive or developmental toxicity studies for acetyl sh‑pentapeptide‑35 were identified; as a synthetic cosmetic peptide it lacks structural alerts for known reproductive toxicants (sources: ECHA Annex VI, SCCS/CIR absence, PubMed/no relevant studies). Topical bioavailability of intact large peptides is negligible for systemic exposure in adults.
Is acetyl sh-pentapeptide-35 safe while breastfeeding?
No data indicating reproductive or lactation-specific toxicity, no harmonised hazard classifications, and no published evidence of breast‑milk transfer for this peptide; systemic exposure from topical use is expected to be negligible in adults (sources: ECHA Annex VI, PubMed, CosIng/PubChem entries showing peptide nature).
Is acetyl sh-pentapeptide-35 safe for baby skin?
No infant-specific reproductive or dermal toxicity data found. Mechanistic concerns are absent, but infant skin has higher permeability: while adult topical absorption of a large acetylated pentapeptide is expected to be negligible, a conservative small increase in exposure (e=1) is applied for 0–3 yr due to immature barrier function (sources: general peptide properties in PubChem/CosIng, lack of toxicology studies in PubMed/ECHA).
How does VeriMom score acetyl sh-pentapeptide-35?
VeriMom scores acetyl sh-pentapeptide-35 at 100/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to acetyl sh-pentapeptide-35?
See our curated list of pregnancy-safe alternatives to acetyl sh-pentapeptide-35 based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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