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Is 3-hexenol safe during pregnancy?

Reviewed by · Last reviewed

Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
3-hexenol
NO KNOWN RISKS
93
/100
0

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Authoritative references used to score this ingredient.

Frequently asked questions

Is 3-hexenol safe during pregnancy?
No harmonised CLP reproductive classification or SCCS/CIR safety assessment was identified; ECHA registration dossier and supplier SDS report an OECD 422 combined repeated-dose/reproduction screening with a NOAEL ≈1000 mg/kg and no specific developmental/teratogenic findings, supporting no reproductive hazard at cosmetic exposure levels (ECHA registration dossier; supplier SDS). PubChem and EWG list the substance but do not report human reproductive evidence. (Sources: ECHA registration page; supplier SDS; PubChem; EWG).
Is 3-hexenol safe while breastfeeding?
Same rationale as pregnancy: no harmonised reproductive classification, no SCCS/CIR opinion, and available animal screening data (OECD 422 NOAEL ~1000 mg/kg) show no reproductive/developmental signal; therefore no specific breastfeeding hazard identified for cosmetic topical use at likely exposures (see ECHA dossier and SDS).
Is 3-hexenol safe for baby skin?
Hazard and mechanism remain unsupported by reproductive/developmental evidence. Exposure was increased by +1 for infants because cis-3-hexenol is a small, somewhat volatile alcohol with measurable dermal/inhalation potential (SDS/ECHA data indicate systemic toxicity only at high doses), and infant skin has higher uptake per body weight—so exposure category is raised from 1 (adult) to 2 (baby 0–3 yr) as requested by the scoring rules.
How does VeriMom score 3-hexenol?
VeriMom scores 3-hexenol at 93/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to 3-hexenol?
See our curated list of pregnancy-safe alternatives to 3-hexenol based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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