Is 1-methylhydantoin-2-imide safe during pregnancy?
Reviewed by VeriMom Editorial Team · Last reviewed
Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
1-methylhydantoin-2-imide
NO KNOWN RISKS100
/100
0![Missha Actibarrier Strong Moist Cream [Intensive]](https://pdi97k8lwqqxczuf.public.blob.vercel-storage.com/products/missha-actibarrier-strong-moist-cream-intensive-N00jVKTrreffgbSBXhcf3hudNIDetw.webp)
![Missha Actibarrier Strong Moist Cream [Sensitive]](https://pdi97k8lwqqxczuf.public.blob.vercel-storage.com/products/missha-actibarrier-strong-moist-cream-sensitive-LgOAqe0yRb64ZlYAqgl1uWQZPfMrf0.webp)








Pregnancy-safe products containing 1-methylhydantoin-2-imide
![Missha Actibarrier Strong Moist Cream [Intensive]](https://pdi97k8lwqqxczuf.public.blob.vercel-storage.com/products/missha-actibarrier-strong-moist-cream-intensive-N00jVKTrreffgbSBXhcf3hudNIDetw.webp)
Missha
Missha Actibarrier Strong Moist Cream [Intensive]
98/100
![Missha Actibarrier Strong Moist Cream [Sensitive]](https://pdi97k8lwqqxczuf.public.blob.vercel-storage.com/products/missha-actibarrier-strong-moist-cream-sensitive-LgOAqe0yRb64ZlYAqgl1uWQZPfMrf0.webp)
Missha
Missha Actibarrier Strong Moist Cream [Sensitive]
98/100

DEMAR3
DEMAR3 Pour-tion 17 Ample
98/100

NO FUSS
NO FUSS Tranexamic Acid Serum
98/100

Missha
Missha Actibarrier Strong Moist Ph Toner
98/100

JM Solution
JM Solution Baby Fresh Sun Cream 40 PA+++
98/100

Umoua
Umoua Polar Lights Extreme Brightening Emulsion
97/100

DEMAR3
DEMAR3 Pour-tion 17 Mist
97/100

AHC
AHC Aqualuronic Serum
97/100

Nivea
Nivea Hyaluron Cellular Filler Nourishing Oil Elixir
96/100
Related ingredients
See also
Sources & references
Authoritative references used to score this ingredient.
Frequently asked questions
- Is 1-methylhydantoin-2-imide safe during pregnancy?
- No harmonised CLP classification or SCCS/CIR reproductive safety concern was found for 1‑methylhydantoin‑2‑imide (CAS 60‑27‑5). Databases identify the substance as creatinine (endogenous metabolite) and list no reproductive/teratogenic findings in regulatory summaries. ECHA substance pages and registration dossier show no harmonised reproduction hazard. (ECHA; PubChem).
- Is 1-methylhydantoin-2-imide safe while breastfeeding?
- No evidence of reproductive or lactation-specific toxicity in regulatory sources or literature searches. The substance is an endogenous, small, water‑soluble molecule (creatinine) with no regulatory lactation warnings or SCCS/CIR restrictions. (ECHA; PubChem).
- Is 1-methylhydantoin-2-imide safe for baby skin?
- No hazard or mechanism indicating developmental/infant-specific toxicity was found. Dermal absorption is expected to be low because the molecule is small and highly water‑soluble; adult exposure is therefore scored negligible (e=0). Following your instruction to increase exposure for infant skin if there is any measurable absorption, baby skin exposure is increased by +1 (e=1). No infant-specific toxicology data were identified. (PubChem; ECHA).
- How does VeriMom score 1-methylhydantoin-2-imide?
- VeriMom scores 1-methylhydantoin-2-imide at 100/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to 1-methylhydantoin-2-imide?
- See our curated list of pregnancy-safe alternatives to 1-methylhydantoin-2-imide based on similar function and a no-known-risks safety band.
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Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.