Безопасен ли withania somnifera root extract при беременности?
Animal reproductive/developmental studies (OECD-style prenatal/developmental studies in Wistar rats) report no maternal or developmental toxicity up to high oral doses (NOEL ≥2000 mg/kg/day), but traditional/ethnobotanical reports describe abortifacient/uterotonic use and some regulatory advisories (e.g., TGA) recommend caution/avoidance in pregnancy. No EU restriction or harmonised CLP reproductive classification was identified. Sources: prenatal/developmental rat study (PubMed), systematic review/ethnobotanical review, and TGA advisory. (PubMed: Prenatal developmental toxicity evaluation; systematic review; TGA advisory).
Безопасные альтернативы withania somnifera root extract при беременности | VeriMom
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- Безопасен ли withania somnifera root extract при беременности?
- Animal reproductive/developmental studies (OECD-style prenatal/developmental studies in Wistar rats) report no maternal or developmental toxicity up to high oral doses (NOEL ≥2000 mg/kg/day), but traditional/ethnobotanical reports describe abortifacient/uterotonic use and some regulatory advisories (e.g., TGA) recommend caution/avoidance in pregnancy. No EU restriction or harmonised CLP reproductive classification was identified. Sources: prenatal/developmental rat study (PubMed), systematic review/ethnobotanical review, and TGA advisory. (PubMed: Prenatal developmental toxicity evaluation; systematic review; TGA advisory).
- Безопасен ли withania somnifera root extract при грудном вскармливании?
- No controlled data demonstrating reproductive or lactation hazards from topical use. LactMed/monograph notes constituents (alkaloids, withanolides) but provides limited data on transfer in human milk; absence of evidence for harm in animal lactation/reproductive studies. Exposure from typical topical cosmetic use is likely low but measurable. Sources: LactMed monograph; animal reproductive studies; lack of regulatory bans.
- Безопасен ли withania somnifera root extract для кожи малыша?
- No infant-specific adverse findings located. Mechanistic or developmental toxicity evidence for topical exposure in infants is lacking; because infant skin has higher absorption, exposure score is increased by +1 relative to adults. No EU Annex II/III listing or harmonised CLP reproductive/teratogenic classification found. Sources: animal studies showing no developmental toxicity, LactMed, regulatory guidance (TGA).
- Как VeriMom оценивает withania somnifera root extract?
- VeriMom оценивает withania somnifera root extract в 67/100 (средний риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы withania somnifera root extract при беременности?
- См. наш список безопасных альтернатив withania somnifera root extract с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.